5251-34-3 Usage
Originator
Syntestan,Syntex,W. Germany,1980
Uses
A systematic corticosteroid. Anti-inflammatory.
Manufacturing Process
A mixture of 5 g of the 21-acetate of 6α-chlorohydrocortisone, 7 g of chloranil
and 100 cc of n-amyl alcohol was refluxed for 16 hours, cooled and diluted
with ether. The solution was successively washed with water, 5% sodium
carbonate solution and water, dried over anhydrous sodium sulfate, filtered
and evaporated to dryness under reduced pressure. Chromatographic
purification of the residue yielded the 21-acetate of 6-chloro-δ1,4,6-
pregnatriene-11β,17α,21-triol-3,20-dione.
Therapeutic Function
Glucocorticoid
Check Digit Verification of cas no
The CAS Registry Mumber 5251-34-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,5 and 1 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5251-34:
(6*5)+(5*2)+(4*5)+(3*1)+(2*3)+(1*4)=73
73 % 10 = 3
So 5251-34-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H25ClO5/c1-19-5-3-11(24)7-14(19)15(22)8-12-13-4-6-21(27,17(26)10-23)20(13,2)9-16(25)18(12)19/h3,5,7-8,12-13,16,18,23,25,27H,4,6,9-10H2,1-2H3/t12-,13-,16-,18+,19-,20-,21-/m0/s1
5251-34-3Relevant articles and documents
Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor
-
, (2008/06/13)
Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.