52532-63-5

Usage

Uses

Used in Pharmaceutical Synthesis:
5-Aminothiophene-2-carbonitrile is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic properties.
Used in Agrochemical Production:
In the agrochemical industry, 5-Aminothiophene-2-carbonitrile is used as a key component in the creation of various agrochemicals, aiding in the development of products designed to enhance crop protection and yield.
Used in Material Science:
5-Aminothiophene-2-carbonitrile is utilized as a building block in material science for its potential to contribute to the development of new materials with unique properties, such as in the creation of organic electronic devices or advanced polymers.
Used in Organic Synthesis:
As a versatile component in organic synthesis, 5-Aminothiophene-2-carbonitrile is used for the synthesis of a wide range of chemical compounds, including those with potential applications in various industries.
Used in Biological Activity Research:
5-Aminothiophene-2-carbonitrile is studied for its potential biological activities, such as antimicrobial and antiviral properties, making it a candidate for use in the development of treatments and preventive measures against infectious diseases.

Upstream product

• 603130-87-6 N-(t-butoxycarbonyl)-5-aminothiophene-2-carbonitrile 
• 16689-02-4 5-nitro-2-thienyl cyanide 

Relevant academic research and scientific papers

MODIFIED PROTEINS AND PROTEIN DEGRADERS

Provided herein are compounds, pharmaceutical compositions, and methods for binding or degrading target proteins. Further provided herein are compounds having a DNA damage-binding protein 1 (DDB1) binding moiety. Some such embodiments include a linker. Some such embodiments include a target protein binding moiety. Further provided herein are ligand-DDB1 complexes. Further provided herein are in vivo modified DDB1 proteins.

SPIROINDOLINONE PYRROLIDINES

There are provided compounds of the formula wherein X, Y and R1 to R8 are described herein along with the enantiomers, pharmaceutically acceptable salts and esters thereof. The compounds are useful as anticancer agents.

METHOD FOR THE PREPARATION OF FUSED HETEROCYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF

Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.

2-Aminothiabutadiene as useful building block in the synthesis of 2-aminothiopyrans and 2-aminothiophenes

We report a reliable and regiocontrolled alternative route to unsubstituted 2-aminothiopyrans and 2-aminothiophenes. These sulfur heterocycles were prepared by reaction of protected aminothiabutadiene 1 with acrylic dienophiles or acceptor-substituted halomethyl compounds. All compounds were fully characterized by IR, HRMS, and 13C and 1H NMR spectroscopy.

Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function

Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.

Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents

This invention relates to 2-arylimino heterocycles, including 2-arylimino-1,3-thiazolidines, 2-arylimino-2,3,4,5-tetrahydro-1,3-thiazines, 2-arylimino-1,3-thiazolidin-4-ones, 2-arylimino-1,3-thiazolidin-5-ones, and 2-arylimino-1,3-oxazolidines, and their use in modulating progesterone receptor mediated processes, and pharmaceutical compositions for use in such therapies.