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525573-25-5

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525573-25-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 525573-25-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,2,5,5,7 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 525573-25:
(8*5)+(7*2)+(6*5)+(5*5)+(4*7)+(3*3)+(2*2)+(1*5)=155
155 % 10 = 5
So 525573-25-5 is a valid CAS Registry Number.

525573-25-5Relevant articles and documents

Synthesis and synthetic applications of 1-aryl-2-alkyl-4,5-dihydro-1 H-imidazoles

Reverdito, Ana M.,Perillo, Isabel A.,Salerno, Alejandra

experimental part, p. 2083 - 2097 (2012/06/01)

An easy synthesis of 1-aryl-2-alkyl-4,5-dihydro-1H-imidazoles 1 by cyclo-condensation of N-acyl-N-arylethylenediamines 2 is described. Such precursors were synthesized by aminolysis of the corresponding N-(2-bromoethyl)amides 3. Cyclizations were performed using trimethylsilyl polyphosphate as a mild dehydrating agent, under microwave irradiation. Chemical properties of 1-aryl-2-alkyl-4,5-dihydro-1H-imidazoles, typical of the amidine system, were studied. Reduction of dihydroimidazoles with sodium cyanoborohydride leads regiospecifically to N-alkyl-N-arylethylenediamines 4, and nucleophilic attack to methyl iodide leads to the corresponding 1-aryl-2-alkyl-3-methyl-4,5-dihydro-1H-imidazolium salts 5.

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