5257-83-0

Basic information

• Product Name: 2-Hydroxy-3-methoxy-1,4-naphthalenedione
• Synonyms: 2-Hydroxy-3-methoxy-1,4-naphthalenedione;2-Hydroxy-3-methoxy-1,4-naphthoquinone;2-hydroxy-3-methoxynaphthalene-1,4-dione
• CAS NO: 5257-83-0
• Molecular Formula: C11H8O4
• Molecular Weight: 204.18
• Mol File: 5257-83-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Hydroxy-3-methoxy-1,4-naphthalenedione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-3-methoxy-1,4-naphthalenedione(5257-83-0)
• EPA Substance Registry System: 2-Hydroxy-3-methoxy-1,4-naphthalenedione(5257-83-0)

Safety Data

• Hazardous Substances Data: 5257-83-0(Hazardous Substances Data)

Upstream product

• 14557-84-7 3-methoxy-1,2-naphthoquinone 
• 116595-16-5 2-benzhydryl-3-methoxy-[1,4]naphthoquinone 
• 77-78-1 dimethyl sulfate 

Relevant articles and documents

Expedient synthesis of 3-hydroxyisoquinolines and 2-hydroxy-1,4- naphthoquinones via one-pot aryne acyl-alkylation/condensation

A convenient method is disclosed for the synthesis of both 3-hydroxyisoquinolines and 2-hydroxy-1,4-naphthoquinones from β-ketoesters using a one-pot aryne acyl-alkylation/condensation procedure. When performed in conjunction with a one-step method for the synthesis of the β-ketoester substrates, this method provides a new route to these polyaromatic structures in only two steps from commercially available carboxylic acid starting materials. The utility of this approach is demonstrated in the synthesis of the atropisomeric P,N-ligand, QUINAP. The Royal Society of Chemistry 2009.