52578-37-7Relevant articles and documents
PYRAZINE DERIVATIVE AND APPLICATION THEREOF IN INHIBITING SHP2
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Paragraph 0140-0141, (2022/01/23)
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Anti-infective compounds
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Page/Page column 47, 48, (2011/08/04)
The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.
4-Hydroxy-2-quinolones 120. Synthesis and structure of ethyl 2-hydroxy-4-oxo-4H-pyrido-[1,2-a]pyrimidine-3-carboxylate
Ukrainets,Bereznyakova,Petyunin,Tugaibei,Rybakov,Chernyshev,Turov
, p. 729 - 739 (2008/03/11)
An improved method for the preparation and purification of ethyl 2-hydroxy-4-oxo-4H-pyrido[1,2-a]-pyrimidine-3-carboxylates is proposed. According to 1H and 13C NMR spectroscopic data the synthesized compounds exist in DMSO solution in the 2-hydroxy-4-oxo form while in the crystal (at least for the case of the unsubstituted derivative) X-ray analysis shows that it occurs in the bipolar 2,4-dioxo form.