52600-50-7Relevant articles and documents
BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS
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Page/Page column 146, (2012/05/20)
The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition Syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by Syk kinase activity, such as Non Hodgkin's Lymphoma.
A Novel Method for the Synthesis of Pyridones
Hawaldar, V. S.,Sunthankar, S. V.
, p. 151 - 152 (2007/10/02)
A novel method for the synthesis of pyridones has been developed.It consists of the reaction of β-dicarbonyl compounds or conjugated enol ethers with cyanoacetamide in the presence of triethylbenzylammonium chloride in aq.NaOH solution.The present method is superior to the literature methods with respect to yield, ease of preparation and absence of organic solvent.