52600-60-9 Usage
Description
5-Acetyl-6-methyl-2-oxo-1,2-dihydro-3-pyridinecarboxamide, commonly known as AMOPAC, is a pyridinecarboxamide derivative with a molecular formula of C9H11N3O2. It features an acetyl and a methyl group attached to the pyridine ring, which contributes to its potential pharmaceutical properties. AMOPAC has been studied for its antifungal and antibacterial activities, as well as its potential in treating neurodegenerative diseases. Furthermore, it serves as a key intermediate in the synthesis of various pharmaceutical compounds, allowing for the development of new drugs with enhanced properties.
Uses
Used in Pharmaceutical Industry:
5-ACETYL-6-METHYL-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXAMIDE is used as an active pharmaceutical ingredient for its antifungal and antibacterial properties, targeting a range of microbial infections. Its unique structure allows it to disrupt the normal functions of fungi and bacteria, thereby inhibiting their growth and proliferation.
Used in Neurodegenerative Disease Treatment:
In the field of neurology, 5-ACETYL-6-METHYL-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXAMIDE is being investigated as a potential therapeutic agent for neurodegenerative diseases. Its specific mechanism of action is still under research, but it may offer neuroprotective effects or modulate pathways implicated in the progression of such diseases.
Used as a Key Intermediate in Drug Synthesis:
5-ACETYL-6-METHYL-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXAMIDE is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its chemical structure can be modified to create new drugs with improved efficacy, safety, or pharmacokinetic profiles, contributing to the advancement of medicinal chemistry.
Used in Drug Development Research:
In the research and development sector, 5-ACETYL-6-METHYL-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXAMIDE serves as a valuable compound for exploring new drug candidates. Its versatile chemical properties make it an attractive starting point for the design and synthesis of novel therapeutic agents targeting a variety of medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 52600-60-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,6,0 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 52600-60:
(7*5)+(6*2)+(5*6)+(4*0)+(3*0)+(2*6)+(1*0)=89
89 % 10 = 9
So 52600-60-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H10N2O3/c1-4-6(5(2)12)3-7(8(10)13)9(14)11-4/h3H,1-2H3,(H2,10,13)(H,11,14)
52600-60-9Relevant articles and documents
Synthesis of substituted nicotinamides from enamines derived from N,N-dimethylformamide dimethyl acetal
Abu-Shanab,Aly,Wakefield
, p. 923 - 925 (1995)
Reactions of 1,3-dicarbonyl compounds with N,N-dimethylformamide dimethyl acetal followed by malonamide in the presence of sodium hydride give 5,6-disubstituted 1,2-dihydro-2-oxopyridine-3-carboxamides 3a-e, whereas reactions of the intermediate enamines with cyanothioacetamide or cyanoacetamide in the presence of piperidine give 4,5-disubstituted 1,2-dihydro-2-thioxopyridine-3-carboxamides 6a-c and 1,2-dihydro-2-oxopyridine-3-carboxamides 6d-h.
5-Acyl-2-(1H)-pyridinones
-
, (2008/06/13)
Novel 5-acyl-2-(1H)pyridinones and their use as cardiotonic agents. Typical of the compounds is 5-acetyl-1,2-dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile which is prepared by condensing anionic cyano acetamide with 3-[(dimethylamino)methylenyl]-2,4-penta
5-Alkyl-1,6-naphthyridin-2(1H)-ones and cardiotonic use thereof
-
, (2008/06/13)
1-R"-3-Q-4-R'-5-R-1,6-naphthyridin-2(1H)-ones (I) or salts thereof, where R is lower-alkyl, R' is hydrogen or methyl, R" is hydrogen or lower-alkyl, and Q is hydrogen, hydroxy, amino, cyano, carbamyl, carboxy or aminocarbamyl, are useful as cardiotonic ag
