52602-64-9Relevant academic research and scientific papers
REACTION OF BENZYL KETONES WITH NITRILES IN PRESENCE OF POCl3
Zielinski, Wojciech
, p. 93 - 100 (2007/10/02)
The reaction of benzyl ketones with nitriles in presence of POCl3 has been examined.It has been found that intermediate N-styrylimidoyl dichlorophosphates formed under reaction conditions undergo further reactions to isoquinoline and pyrimidine derivatives and form the products of fragmentation and condensation.The effect of structure of the substrates on the relative ratios of the products formed has been discussed.
