52610-46-5

Upstream product

• 17522-32-6 (S)-dehydro-α-damascol 
• 13395-71-6 2,4,4-trimethyl-2-cyclohexenone 
• 37079-64-4 1-<3-(2,6,6-Trimethyl-2-cyclohexen-1-yl)oxiranyl>ethanone 
• 139609-01-1 α-Methyl-3-(2,6,6-trimethyl-2-cyclohexen-1-yl)oxiranemethanol 
• 127-41-3 alpha-ionone 
• 139609-03-3 2-(1-Bromoethyl)-3-(2,6,6-trimethyl-2-cyclohexen-1-yl)oxirane 
• 134780-16-8 (R)-2,4,4-trimethyl-2-cyclohexen-1-ol 
• 14505-74-9 (S)-2,6,6-trimethylcyclohex-2-enecarbaldehyde 
• 52646-93-2 [(S)-2,6,6-trimethylcyclohex-2-enyl]methanol 
• 37079-64-4 1-[3-(2,6,6-trimethyl-cyclohex-2-enyl)-oxiranyl]-ethanone 
• 124572-59-4 α-ionone epoxyhydrazone 

Downstream Products

• 116497-11-1 (2E)-1-[(S)-2,6,6-trimethylcyclohex-2-enyl]but-2-en-1-one 
• 23726-94-5 (Z)-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one 
• 24720-09-0 α-damascone 
• 127-41-3 alpha-ionone 
• 57549-92-5 ⁽²⁾-1-(2,6,6-trimethylcyclohex-2-en-1-yl)butan-1-one 

Relevant academic research and scientific papers

APPLICATION OF BIOCHEMICAL METHODS IN ENANTIOSELECTIVE SYNTHESIS OF BIOACTIVE NATURAL PRODUCTS

Enzymes as well as yeasts were used in enantioselective syntheses of bioregulators such as hormones and semiochemicals.Lipases and esterases were employed in achieving optical resolution, conversion of meso-compounds to optically active compounds, and macrolactonization.Lactase effected glucosidation of a phenolic hydroxy ketone without any protection of the functional groups.Yeasts provided a variety of optically active hydroxy esters and ketones, which served as versatile non-racemic chiral building blocks.

NEW DEVELOPMENTS OF THE WHARTON TRANSPOSITION

The synthetically useful Wharton transposition can be improved by using a more adequate procedure in the critical step of the intermediate α-epoxyhydrazone cleavage.Either for stable hydrazones or unstable ones, the yield of the transposed allylic alcohol is increased by treatment under anhydrous conditions with highly basic reagents (KDA in the former case, NEt3 in the latter).

Alkenoyl-cyclohexadienes

New cycloaliphatic unsaturated ketones and their use as perfuming and odour-modifying agents in the manufacture of perfumes and perfumed products, and as flavouring and taste-modifying agents in the preparation of foodstuffs in general and imitation flavours for foodstuffs, beverages, animal feeds, pharmaceutical preparations and tobacco products. Methods for the preparation of said cycloaliphatic unsaturated ketones.