526214-14-2Relevant academic research and scientific papers
Synthesis of tert-alkyl amino hydroxy carboxylic esters via an intermodular ene-type reaction of oxazolones and enol ethers
Mosey, Robert A.,Fisk, Jason S.,Friebe, Timothy L.,Tepe, Jetze J.
supporting information; experimental part, p. 825 - 828 (2009/04/07)
terf-Alkyl amino hydroxy carboxylic acids are abundantly present within the structure of many biologically active natural products. We describe herein the synthesis of these substrates using an oxazolone-mediated ene-type reaction with enol ethers followed by NaBH4 reduction of the intermediate oxazolone.
