526217-54-9Relevant academic research and scientific papers
Novel route to the synthesis of peptides containing 2-amino-1′-hydroxymethyl ketones and their application as cathepsin K inhibitors
Mendonca, Rohan V,Venkatraman, Shankar,Palmer, James T.
, p. 2887 - 2891 (2007/10/03)
Cathepsin K is highly expressed in human osteoclasts, and is implicated in bone resorption. This makes it an attractive target for the treatment of osteoporosis. Peptides containing 2-amino-1′-hydroxymethyl ketones and 2-amino-1′-alkoxymethyl ketones were
