526223-05-2

Upstream product

• 526223-00-7 (2S,4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-pyrrolidine-1,2,4-tricarboxylic acid 1-benzyl ester 2-tert-butyl ester 
• 526223-01-8 (2S,4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-pyrrolidine-1,2,4-tricarboxylic acid 1-benzyl ester 2-tert-butyl ester 4-methyl ester 
• 526222-98-0 (5S,8S)-2,4-dioxo-1,3,7-triazaspiro[4.4]nonane-1,3,7,8-tetracarboxylic acid 7-benzyl ester 1,3,8-tri-tert-butyl ester 
• 526222-96-8 (5S,8S)-2,4-dioxo-1,3,7-triazaspiro[4.4]nonane-7,8-dicarboxylic acid 7-benzyl ester 8-tert-butyl ester 
• 526222-99-1 (3S,5S)-1-((benzyloxy)carbonyl)-5-(tert-butoxycarbonyl)-3-aminopyrrolidine-3-carboxylic acid 

Downstream Products

• 526223-06-3 C₂₉H₃₈N₈O₁₀ 

Relevant academic research and scientific papers

The synthesis of functionalized nanoscale molecular rods of defined length

We report a synthetic approach to spiro-ladder oligomers of defined length and structure that form water-soluble molecular rods. We describe the synthesis of a chiral molecular building block 1 and its assembly on solid support to form flexible chains that were then rigidified by the parallel formation of several diketopiperazine rings. Two molecular rods approximately 15 and 25 A in length were synthesized containing three and five monomers, respectively. The molecular rods were easily functionalized on both ends and were shown to have high water solubility, making them compatible with biological buffers. These molecules may find use as scaffolds for the display of ligands in chemical-biology applications and as spacers and construction materials for nanoscience applications. Copyright