52643-93-3

Usage

Derivative of

indenol

Functional Groups

amino group, two methoxy groups
Not naturally occurring
Primarily used in research and drug development
Potential applications in pharmaceutical industry
Used for synthesis of biologically active compounds

Upstream product

• 80632-90-2 2-amino-4,5-dimethoxy-1-indanone 
• 37096-36-9 2-amino-4,5-dimethoxyindan-1-one hydrochloride 

Downstream Products

• 94077-23-3 (1S,2R)-2-(3,4-Dimethoxy-benzylamino)-4,5-dimethoxy-indan-1-ol 

Relevant academic research and scientific papers

Unusual Transposition of the Carbonyl Group in the Reduction of 2-Amino-1-indanone

The catalytic reduction procedure of 2-amino-4,5-dimethoxy-1-indanone hydrochloride gave a major reduction product of 2-amino-4,5-dimethoxyindan hydrochloride, along with a small amount of a rearranged 4,5-dimethoxy-2-indanone.The isolated intermediate, 2-amino-4,5-dimethoxy-1-indanol hydrochloride yielded exclusively 4,5-dimethoxy-2-indanone under catalytic reaction conditions (acid treatment).The unusual transformation product was verified on the basis of IR, NMR and the result of elemental analysis.A plausible mechanism for the rearrangement is discussed.

Synthesis and C.d. Spectra of 6,6a,7,11b-tetrahydro-5H-indenoisoquinoline Derivatives

We have synthesized the title compounds having two pharmacophores of the β-phenethylamine moiety with a semi-rigid spatial arrangement.They are very suitable for studies on the limit of the effect of electron exchange between two aromatic chromophores.X-R