52648-76-7Relevant academic research and scientific papers
Method for synthesizing alpha-fluoro-alpha-substituted ketone of fluorine-containing quaternary carbon central structure
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Paragraph 0112; 0113; 0114; 0115; 0116; 0117, (2019/02/04)
The invention discloses a method for synthesizing alpha-fluoro-alpha-substituted ketone of a fluorine-containing quaternary carbon central structure. The method comprises the following step: under catalysis of an acid, enabling alpha-substituted ketone to
p-Toluenesulfonic acid catalysed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centres
Tang, Shi-Zhong,Bian, Hong-Li,Zhan, Zong-Song,Chen, Meng-En,Lv, Jian-Wei,Xie, Shaolei,Zhang, Fu-Min
supporting information, p. 12377 - 12380 (2018/11/30)
A p-toluenesulfonic acid catalyzed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centers has been developed, featuring a broad substrate scope, environmentally benign reaction conditions, and operational simplicity.
