5266-55-7 Usage
Description
1-(4-methoxy-2,3-dimethylbenzyl)-4-methyl-1,4-diazepane is a chemical compound characterized by a diazepane ring structure. It features a benzyl group substituted with a methoxy and two methyl groups, along with a methyl group at the 4-position of the diazepane ring. 1-(4-methoxy-2,3-dimethylbenzyl)-4-methyl-1,4-diazepane is of interest in medicinal and pharmaceutical research due to its potential applications in the development of new drugs and therapeutic treatments.
Uses
Used in Pharmaceutical Research:
1-(4-methoxy-2,3-dimethylbenzyl)-4-methyl-1,4-diazepane is used as a research compound for its potential in developing new drugs and therapeutic treatments. Its unique structure and functional groups make it a promising candidate for further study and possible applications in various medical fields.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(4-methoxy-2,3-dimethylbenzyl)-4-methyl-1,4-diazepane is utilized as a structural component in the design and synthesis of novel pharmaceutical agents. Its specific functional groups and ring structure contribute to its potential as a building block for creating effective and targeted medications.
Used in Drug Development:
1-(4-methoxy-2,3-dimethylbenzyl)-4-methyl-1,4-diazepane is employed as a key component in drug development, where its properties can be harnessed to create new therapeutic agents. 1-(4-methoxy-2,3-dimethylbenzyl)-4-methyl-1,4-diazepane's structural features may offer advantages in terms of selectivity, potency, and pharmacokinetics, which are critical factors in the development of successful drugs.
Used in Chemical Synthesis:
In the chemical synthesis industry, 1-(4-methoxy-2,3-dimethylbenzyl)-4-methyl-1,4-diazepane serves as an intermediate or a starting material for the synthesis of more complex molecules with specific applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Used in Drug Design:
1-(4-methoxy-2,3-dimethylbenzyl)-4-methyl-1,4-diazepane is used as a structural element in drug design, where its unique properties can be leveraged to create molecules with improved pharmacological profiles. Its incorporation into drug candidates may lead to enhanced efficacy, reduced side effects, or novel mechanisms of action.
Check Digit Verification of cas no
The CAS Registry Mumber 5266-55-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,6 and 6 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5266-55:
(6*5)+(5*2)+(4*6)+(3*6)+(2*5)+(1*5)=97
97 % 10 = 7
So 5266-55-7 is a valid CAS Registry Number.
5266-55-7Relevant articles and documents
Inhibition of the Mammalian β-Lactamase Renal Dipeptidase (Dehydropeptidase-I) by (Z)-2-(Acylamino)-3-substituted-propenoic Acids
Graham, Donald W.,Ashton, Wallace T.,Barash, Louis,Brown, Jeannette E.,Brown, Ronald D.,et al.
, p. 1074 - 1090 (2007/10/02)
The title enzyme deactivates the potent carbapenem antibiotic imipenem in the kidney, producing low antibiotic levels in the urinary tract.A series of (Z)-2-(acylamino)-3-substituted-propenoic acids (3) are specific, competitive inhibitors of the enzyme capable of increasing the urinary concentration of imipenem in vivo.Many of the compounds were prepared in one step from an α-keto acid and a primary amide.The optimum R2 groups are 2,2-dimethyl, -dichloro, and -dibromocyclopropyl.With R2 = 2,2-dimethylcyclopropyl (DMCP), a wide variety of R3 groups including alkyl, oxa- and thiaalkyl, and alkyl groups containing acidic, basic, and neutral substituents give effective inhibitors with Ki values of 0.02-1 μM and a range of pharmacokinetic properties.By resolution of enantiomers and X-ray crystallography, the enzyme-inhibitory activity of the DMCP group was found to reside with the 1S isomer.The cysteinyl compound 176 (cilastatin, MK-0791) has the desired pharmacological properties and has been chosen for combination with imipenem.
