52662-40-5

Basic information

• Product Name: 3(2H)-Furanone, dihydro-2,2-dimethyl-
• Synonyms: 3(2H)-Furanone,dihydro-2,2-dimethyl
• CAS NO: 52662-40-5
• Molecular Formula: C6H10O2
• Molecular Weight: 114.14200
• Mol File: 52662-40-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3(2H)-Furanone, dihydro-2,2-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Furanone, dihydro-2,2-dimethyl-(52662-40-5)
• EPA Substance Registry System: 3(2H)-Furanone, dihydro-2,2-dimethyl-(52662-40-5)

Safety Data

• Hazardous Substances Data: 52662-40-5(Hazardous Substances Data)

Upstream product

• 35298-48-7 2,2-dimethyl-3(2H)-furanone 
• 35298-49-8 2-hydroxy-5,5-dimethyltetrahydrofuran-4-one 
• 115-22-0 3-Hydroxy-3-methyl-2-butanone 
• 22082-43-5 2-hydroxy-2-methyl-pent-4-en-3-one 
• 2425-45-8 4-methylpenta-2,3-dien-1-ol 
• 74087-85-7 3,3-dimethyldioxirane 

Downstream Products

• 142996-71-2 4-hydroxymethylene-dihydro-2,2-dimethyl-3(2H)furanone 
• 106017-77-0 2,2-dimethyl-1,3-dioxan-4-one 

Relevant articles and documents

ALLENE EPOXIDATION. OXIDATIVE CYCLIZATIONS OF ALLENYL ALCOHOLS

The dimethyldioxirane oxidation of various allenic alcohols yields highly functionalized tetrahydrofuran and tetrahydropyran derivatives via intramolecular nucleophilic addition of the hydroxy group to an intermediate allene diepoxide.

Pheromone synthesis. Part 264: Synthesis of the core 3-oxabicyclo[3.3.0]octane structures of gomadalactones A, B and C, the components of the contact sex pheromone of the white-spotted longicorn beetle, Anoplophora malasiaca

The core bicyclic cyclopentanelactone structures of gomadalactones A, B and C with α-hydroxyketone system were synthesized from (R)-pulegone, employing deconjugation of an α,β-unsaturated lactone as the key step. Comparison of the CD spectra of the synthetic compounds with those of the natural products confirmed the absolute configuration of the natural pheromone components as proposed in 2007. X-ray crystallographic analysis of the model compound of gomadalactone B core structure was carried out.

QUINAZOLIN-THF-AMINES AS PDE1 INHIBITORS

The present invention provides Quinazolin-THF-amines as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.