52665-49-3

Usage

Uses

Used in Pharmaceutical Industry:
Furan-3-sulfonyl chloride is used as a reagent in the synthesis of pharmaceuticals for its ability to form covalent bonds with a variety of organic compounds. It plays a crucial role in the production of sulfonamides, which are important pharmacological agents.
Used in Agrochemical Industry:
In the agrochemical industry, Furan-3-sulfonyl chloride is used as an intermediate in the production of various agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals.
Used in Organic Synthesis:
Furan-3-sulfonyl chloride is used as a reagent in organic synthesis for its strong sulfonating ability, making it a valuable tool in the modification of organic molecules for various industrial applications.
It is important to handle Furan-3-sulfonyl chloride with caution due to its corrosive nature, which can cause severe skin and eye irritation. Proper safety measures should be taken during its use to ensure the safety of individuals and the environment.

InChI:InChI=1/C4H3ClO3S/c5-9(6,7)4-1-2-8-3-4/h1-3H

Upstream product

• 22037-28-1 3-bromofurane 

Downstream Products

• 909897-05-8 methyl 4-{[2-[(3-furylsulfonyl)amino]-5-(trifluoromethyl)phenoxy]methyl}benzoate 
• 1040279-97-7 N-(3-amino-8-chloro-1-phenyl-5,6-dihydrobenzo[f]quinazolin-9-yl)furan-3-sulfonamide 
• 1141802-54-1 N-{4-[3-(1,2-O-isopropylidene-D-ribotetritol-1-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]phenyl}furan-3-sulfonamide 
• 1138036-36-8 2-(2-fluorophenyl)-1-(furan-3-ylsulfonyl)-1H-imidazole-4-carbaldehyde 
• 1269500-24-4 C₁₉H₂₅N₃O₆S 
• 1380228-95-4 N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)furan-3-sulfonamide 
• 1383745-20-7 C₁₂H₁₀ClFN₂O₄S 
• 1195769-75-5 1,1-dimethylethyl 4-(5-(2-chloro-4-pyrimidinyl)-4-{2-fluoro-3-[(3-furanylsulfonyl)amino]phenyl}-1,3-thiazol-2-yl)-1-piperidinecarboxylate 
• 1195769-67-5 1,1-dimethylethyl 4-(5-(2-chloro-4-pyrimidinyl)-4-{2-fluoro-3-[(3-furanylsulfonyl)amino]phenyl}-1,3-thiazol-2-yl)-4-methyl-1-piperidinecarboxylate 
• 1195769-61-9 1,1-dimethylethyl [1-(5-(2-chloro-4-pyrimidinyl)-4-{2-fluoro-3-[(3-furanylsulfonyl)amino]phenyl}-1,3-thiazol-2-yl)-1-methylethyl]carbamate 

Relevant academic research and scientific papers

SULFONAMIDE INHIBITORS OF ASPARTYL PROTEASE

The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention and methods for screening compounds for anti-HIV activity.

SULFONAMIDE INHIBITORS OF ASPARTYL PROTEASE

The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention and methods for screening compounds for anti-HIV activity.