52683-82-6Relevant articles and documents
Michael Addition of 2,2-Difluoroketene Silyl Acetal. Preparation of 4,4-Difluoroglutamic Acid and 5,5-Difluorolysine
Kitagawa, Osamu,Hashimoto, Akihiro,Kobayashi, Yoshiro,Taguchi, Takeo
, p. 1307 - 1310 (2007/10/02)
2,2-Difluoroketene Silyl Acetal, generated in situ by treating methyl difluoroiodoacetate with Zn followed by chlorosilane, readily reacted with α,β-unsaturated carbonyl compounds or acetals to give the 1,4-addition products, preferentially.The difluoro a