527-09-3 Usage
Description
Copper(II) gluconate is the copper salt of D-gluconic acid that is an organic acid. It can be used as a buffer for encapsulating some drugs into liposomes. Copper is an essential microelement for human beings and animals; it is needed to absorb ion from and gut and can help regulate blood pressure and heart rate. It is also a key component of multiple enzymes involved in many biochemical reactions. In this sense, the D-gluconic acid copper (II) salt can be used as a copper supplement to treat the copper deficiency induced anemia and nephrosis. It is also useful in the cancer chemotherapy being capable of enhancing the efficacy of the anticancer drug, disulfiram.
References
Dicko, Awa, et al. "Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes." International Journal of Pharmaceutics 337.1(2007):219-228.
Ferris Iii, Frederick L, et al. "Nutritional supplement to treat macular degeneration.", EP1516542. 2009.
Georgewill Udeme Owunari, Siminialayi Iyeopu Minakiri. “Disulfiram and Copper gluconate in cancer chemotherapy: a review of the literature.” Cancer Research Journal 2.5(2014):88-92.
Chemical Properties
Copper(II) gluconate, Cu(C6H11O7)2, is a light blue to blue-green, crystalline material that is soluble in water and slightly soluble in ethanol.
Uses
Different sources of media describe the Uses of 527-09-3 differently. You can refer to the following data:
1. copper gluconate is cited as having skin-conditioning and skinprotecting functions.
2. Copper(II) gluconate is used in dietary supplement. It is also used to treat acne vulgaris, common cold, hypertension, premature labor, leishmaniasis and visceral postoperative complications. Further, it is used in oral deodorants and feed additives. In addition to this, it is used as a synergist and nutritional supplement for foods. It is the active component in retsyn used in mints and certs.
Preparation
Copper(II) gluconate is prepared by the dissolution of copper(II) carbonate or copper(II) hydroxide in gluconic acid. It is used as a nutritional supplement for copper deficiency and as a component in oral deodorants.
Flammability and Explosibility
Notclassified
Safety Profile
When heated to
decomposition it emits acrid smoke and
irritating fumes.
Check Digit Verification of cas no
The CAS Registry Mumber 527-09-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 527-09:
(5*5)+(4*2)+(3*7)+(2*0)+(1*9)=63
63 % 10 = 3
So 527-09-3 is a valid CAS Registry Number.
InChI:InChI=1/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1/rC12H22CuO14/c14-1-3(16)5(18)7(20)9(22)11(24)26-13-27-12(25)10(23)8(21)6(19)4(17)2-15/h3-10,14-23H,1-2H2/t3-,4-,5-,6-,7+,8+,9-,10-/m1/s1
