52763-25-4

Upstream product

• 702-15-8 3-(4-fluorophenyl)propan-1-ol 
• 24484-55-7 1-bromo-3-(4-fluorophenyl)propane 
• 39151-19-4 1-(3,5-dimethoxyphenyl)ethan-1-one 

Downstream Products

• 52763-26-5 2-(3,5-dihydroxyphenyl)-5-(4-fluorophenyl)pentane 

Relevant academic research and scientific papers

5H-[1]Benzopyrano[3,4-d]pyridines

5H-[1]Benzopyrano[3,4-d]pyridines represented by the formula STR1 wherein each R1 is loweralkyl, R2 is alkyl, cycloalkyl or STR2 wherein Y is a straight or branched chain alkylene group having from 1 to 10 carbon atoms and each Rsub

Heterocyclic esters of alkylphenyl benzopyranopyridines

Heterocyclic esters of alkylphenyl benzopyranopyridines represented by the formula STR1 wherein R1 is hydrogen, loweralkyl, loweralkanoyl, cycloalkylloweralkyl, cycloalkylloweralkanoyl, loweralkenyl, loweralkynyl, haloloweralkenyl, phenylloweralkyl, phenylloweralkenyl or phenylloweralkynyl; R2 is loweralkyl; R3 is STR2 WHEREIN X is a straight or branched chain alkylene group having from one to eight carbon atoms, a is an integer from 1 to 4, b is an integer from 1 to 4 and Z is CH2, O, S or NR7, with R7 being hydrogen or loweralkyl, with the limitation that when X is O, S or NR7, the sum of a and b is 3 or 4; and R8 is hydrogen or loweralkyl; Y is a straight or branched chain alkylene group having from one to ten carbon atoms; and each R4 and R5 and R6 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl; and the pharmaceutically acceptable acid addition salts thereof.

Alkylphenyl benzopyranopyridines

Alkylphenyl benzopyranopyridines represented by the formula STR1 where R1 is hydrogen, loweralkyl, loweralkanoyl, cycloalkylloweralkyl, cycloalkylloweralkanoyl, loweralkenyl, loweralkynyl, haloloweralkenyl, phenylloweralkyl, phenylloweralkenyl or phenylloweralkynyl; R2 is loweralkyl; R3 is hydrogen; Y is a straight or branched chain alkylene group having from one to ten carbon atoms; and each R4 and R5 and R6 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl; and the pharmaceutically acceptable salts thereof.

8-Aralkyl-1,4-ethano-5H-[1]benzopyrano[3,4-b]pyridines

A new series of 8-aralkyl-1,4-ethano-5H-[1]benzopyrano[3,4-b]pyridines having anti-convulsant activity, and compounds useful in the preparation thereof. The compounds are represented by the formula STR1 wherein each R1 is loweralkyl; R2/s

Anesthesia methods using benzopyrans and esters thereof as pre-anesthesia medication

Improved anesthesia methods comprising pretreating a patient to be anesthetized with a benzopyran of formula I STR1 wherein, in the C ring, X is NR1, S, CH2 or STR2 R1 is hydrogen, loweralkyl, loweralkenyl, loweralkynyl, loweralkanoyl, cycloalkyloweralkyl, cycloalkylloweralkanoyl, cycloalkyl, haloloweralkyl, haloloweralkenyl, phenylloweralkyl, phenyloweralkenyl or phenyloweralkylnyl; m is an integer from 0 to 3, n is an integer from 0 to 3 and n + m = 2 or 3; or the C ring is quinuclidine ring STR3 R2 is loweralkyl; R3 is hydrogen or STR4 wherein Y is a straight or branched chain alkylene group having from one to eight carbon atoms, a is an integer from 1 to 4, b is an integer from 1 to 4, Z is CH2, O, S or NR6, R6 being hydrogen or loweralkyl, with the limitation that when Z is O, S or NR5, the sum of a and b is 3 or 4, and R5 is hydrogen or loweralkyl; R4 is C1 -C20 straight or branched chain alkyl, cycloalkyl, or STR5 wherein Y is a straight or branched chain alkylene group having from one to ten carbon atoms, and each R7, R8 and R9 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl; and the pharmaceutically acceptable salts thereof, with the limitation that when X is STR6 m = 2 and n = 2, R3 cannot be hydrogen.

Drugs derived from cannabinoids. 5. Δ(6a,10a) Tetrahydrocannabinol and heterocyclic analogs containing aromatic side chains

Ten new Δ(6a,10a) THC analogs with arylalkyl side chains, one with a dimethylaminoalkyl side chain, and six heterocyclic Δ(6a,10a) THC analogs [8 substituted 5,5 dimethyl 10 hydroxy 2 (2 propynyl) 1,2,3,4 tetrahydro 5H [1] benzo pyranol [4,3 c] pyridines] were prepared. They showed pharmacological activity as analgesics, tranquilizers, antihypertensives, and hypnotics and as antisecretory, antiulcer, and antidiarrheal agents. The most potent compounds had either a 1 methyl 4 (4 fluorophenyl) butyl or a 1,2 dimethyl 4 (4 fluorophenyl) butyl side chain.

Alkylphenyl benzopyranopyridines

Alkylphenyl benzopyranopyridines represented by the formula SPC1 Where R1 is hydrogen, loweralkyl, loweralkanoyl, cycloalkylloweralkyl, cycloalkylloweralkanoyl, loweralkenyl, loweralkynyl, haloloweralkenyl, phenylloweralkyl, phenylloweralkenyl or phenylloweralkynyl; R2 is loweralkyl; R3 is hydrogen; Y is a straight or branched chain alkylene group having from one to ten carbon atoms; and each R4 and R5 and R6 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl; and the pharmaceutically acceptable salts thereof.

2,4,7-substituted 5-hydroxy benzopyrans and esters

2,4,7-Substituted 5-hydroxy benzopyrans and dihydrobenzopyrans and their esters represented by the formulae SPC1 Wherein each R1 is loweralkyl, and R2 is hydrogen, loweralkanoyl or SPC2 With Y being a straight or branched chain alkylene group having from 1-8 carbon atoms; a is an integer from 1-4; b is an integer from 1-4; X is CH2, O, S, or NR5 with R5 being hydrogen or loweralkyl, with the limitation that when X is O, S, or NR5, the sum of a and b is 3 or 4 and R4 is hydrogen or loweralkyl; and R3 is SPC3 With Y' being a straight or branched chain alkylene group having from 1-10 carbon atoms; and each R7, R8 and R9 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl and the pharmaceutically acceptable salts thereof.