Cas 527678-06-4,(S)-2-{4-[(5S,5aS,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxy-phenyl)-8-oxo-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-ylamino]-benzoylamino}-3-(1H-indol-3-yl)-propionic acid methyl ester

527678-06-4

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Basic information

Product Name: (S)-2-{4-[(5S,5aS,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxy-phenyl)-8-oxo-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-ylamino]-benzoylamino}-3-(1H-indol-3-yl)-propionic acid methyl ester
Synonyms: (S)-2-{4-[(5S,5aS,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxy-phenyl)-8-oxo-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-ylamino]-benzoylamino}-3-(1H-indol-3-yl)-propionic acid methyl ester
CAS NO:527678-06-4
Molecular Formula:
Molecular Weight: 719.748
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (S)-2-{4-[(5S,5aS,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxy-phenyl)-8-oxo-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-ylamino]-benzoylamino}-3-(1H-indol-3-yl)-propionic acid methyl ester(CAS DataBase Reference)
NIST Chemistry Reference: (S)-2-{4-[(5S,5aS,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxy-phenyl)-8-oxo-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-ylamino]-benzoylamino}-3-(1H-indol-3-yl)-propionic acid methyl ester(527678-06-4)
EPA Substance Registry System: (S)-2-{4-[(5S,5aS,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxy-phenyl)-8-oxo-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-ylamino]-benzoylamino}-3-(1H-indol-3-yl)-propionic acid methyl ester(527678-06-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 527678-06-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 527678-06-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,2,7,6,7 and 8 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 527678-06:
(8*5)+(7*2)+(6*7)+(5*6)+(4*7)+(3*8)+(2*0)+(1*6)=184
184 % 10 = 4
So 527678-06-4 is a valid CAS Registry Number.

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527678-06-4Relevant academic research and scientific papers

Antitumor agents. Part 227: Studies on novel 4′-O-demethyl- epipodophyllotoxins as antitumor agents targeting topoisomerase II

Xiao, Zhiyan,Bastow, Kenneth F.,Vance, John R.,Lee, Kuo-Hsiung

, p. 3339 - 3344 (2004)

Eight novel epipodophyllotoxin derivatives (6-13), which were designed to overcome drug resistance and enhance topoisomerase II inhibition, were synthesized and evaluated. Two of these compounds (7 and 8) showed better preclinical activity profiles, inclu

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