52773-23-6 Usage
Description
1-(1,3-DIMETHYL-1 H-PYRAZOL-4-YL)-ETHANONE, also known as 4-acetyl-1,3-dimethylpyrazole, is a pyrazole derivative with a molecular formula C7H10N2O. It is a colorless to pale yellow liquid with a pungent odor, insoluble in water but soluble in organic solvents. This chemical compound is utilized as a precursor in the synthesis of various pharmaceuticals, fragrances, and agrochemicals, making it a versatile component in different industries.
Uses
Used in Pharmaceutical Industry:
1-(1,3-DIMETHYL-1 H-PYRAZOL-4-YL)-ETHANONE is used as a precursor in the synthesis of pharmaceuticals for its ability to contribute to the development of new medicinal compounds. Its unique structure allows it to be a key component in creating drugs with specific therapeutic properties.
Used in Fragrance Industry:
In the fragrance industry, 1-(1,3-DIMETHYL-1 H-PYRAZOL-4-YL)-ETHANONE is used as a precursor for creating various scent compounds. Its pungent odor and solubility in organic solvents make it suitable for developing complex and long-lasting fragrances.
Used in Agrochemical Industry:
1-(1,3-DIMETHYL-1 H-PYRAZOL-4-YL)-ETHANONE is utilized as a precursor in the development of agrochemicals, specifically in the synthesis of pesticides and other agricultural chemicals. Its role in these products is crucial for enhancing crop protection and yield.
It is important to handle 1-(1,3-DIMETHYL-1 H-PYRAZOL-4-YL)-ETHANONE with caution and proper safety measures due to its chemical properties, as with any other chemical substance. Limited studies are available on its specific properties and uses, emphasizing the need for ongoing research and responsible application in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 52773-23-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,7,7 and 3 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 52773-23:
(7*5)+(6*2)+(5*7)+(4*7)+(3*3)+(2*2)+(1*3)=126
126 % 10 = 6
So 52773-23-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2O/c1-5-7(6(2)10)4-9(3)8-5/h4H,1-3H3
52773-23-6Relevant articles and documents
Toward Continuous-Flow Synthesis of Biologically Interesting Pyrazole Derivatives
Das, Amrita,Ishitani, Haruro,Kobayashi, Shū
supporting information, p. 5127 - 5132 (2019/11/13)
A two-step continuous-flow synthesis of substituted pyrazole derivatives has been developed via the formation of vinylidene keto esters as key intermediates. Heterogeneous Ni2+-montmorillonite was found to be an efficient catalyst for orthoester condensation of 1,3-dicarbonyls under flow conditions. The intermediate reacted with methylhydrazine to afford pyrazole derivatives, for which suitable selection of a solvent played a key role in achieving high yields and excellent regioselectivities of the desired products. An application of this protocol has been demonstrated by the synthesis of a key intermediate for biologically active pyrazoles such as Bixafen. (Figure presented.).
TETRAHYDROPYRAZOLOPYRIMIDINE COMPOUNDS
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Paragraph 0513, (2014/01/07)
Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis
Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists
Altenbach, Robert J.,Liu, Huaqing,Banfor, Patricia N.,Browman, Kaitlin E.,Fox, Gerard B.,Fryer, Ryan M.,Komater, Victoria A.,Krueger, Kathleen M.,Marsh, Kennan,Miller, Thomas R.,Jia, Bao Pan,Pan, Liping,Sun, Minghua,Thiffault, Christine,Wetter, Jill,Zhao, Chen,Zhou, Deliang,Esbenshade, Timothy A.,Hancock, Arthur A.,Cowart, Marlon D.
, p. 5439 - 5448 (2008/03/13)
A new structural series of histamine H3 receptor antagonist was developed. The new compounds are based on a quinoline core, appended with a required basic aminoethyl moiety, and with potency- and property-modulating heterocyclic substituents. The analogs
