52782-40-8Relevant academic research and scientific papers
Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents
Honda, Tadashi,Yoshizawa, Hidenori,Sundararajan, Chitra,David, Emilie,Lajoie, Marc J.,Favaloro Jr., Frank G.,Janosik, Tomasz,Su, Xiaobo,Honda, Yukiko,Roebuck, Bill D.,Gribble, Gordon W.
supporting information; experimental part, p. 1762 - 1778 (2011/05/28)
Forty-four novel tricycles containing nonenolizable cyano enones (TCEs) were designed and synthesized on the basis of a semisynthetic pentacyclic triterpenoid, bardoxolone methyl, which is currently being developed in phase II clinical trials for the trea
Enantiospecific total synthesis of (+)- and (-)-avarone and -avarol
Locke, Edward P.,Hecht, Sidney M.
, p. 2717 - 2718 (2007/10/03)
Enantiopure avarol and its oxidized congener avarone are synthesized in both podal series from an optically pure Wieland-Miescher enone; preliminary results from biochemical studies are summarized.
