52788-64-4Relevant academic research and scientific papers
Reusable and efficient CuI/TBAB-catalyzed iodination of terminal alkynes in water under air
Chen, Shao-Nung,Hung, Tzu-Ting,Lin, Tze-Chiao,Tsai, Fu-Yu
, p. 1078 - 1081 (2009)
An environmentally-friendly and operationally-simple process for the synthesis of 1-iodoalk-1-ynes under mild conditions catalyzed by CuI/TBAB in water under air was developed in this study. Catalyst loadings of CuI as low as 1-2 mol% gave 1-iodoalk-1-yne
Acetic Acid Promoted Direct Iodination of Terminal Alkynes with N -Iodosuccinimide: Efficient Preparation of 1-Iodoalkynes
Liu, Liu E.,Xiong, Hangxing,Yang, Sen,Yao, Ming,Zhang, Jingjing
supporting information, p. 1102 - 1106 (2020/07/04)
An efficient and highly chemoselective approach for the direct iodination of terminal alkynes using acetic acid as N -iodosuccinimide activated reagent under metal-free conditions has been developed. This facile process tolerates a variety of terminal alkynes and provides the desired products in good to excellent yields (up to 99percent).
Efficient synthesis of 1-iodoalkynes: Via Al2O3 mediated reaction of terminal alkynes and N -iodosuccinimide
Yao, Ming,Zhang, Jingjing,Yang, Sen,Xiong, Hangxing,Li, Li,Liu,Shi, Hong
, p. 3946 - 3950 (2020/02/04)
Iodination of terminal alkynes using N-iodosuccinimide (NIS) in the presence of γ-Al2O3 was developed to afford 1-iodoalkynes with good to excellent yields (up to 99%). This described approach featured excellent chemoselectivity, good functional group tolerance, and utilization of an inexpensive catalyst.
Oxidative Addition of Alkenyl and Alkynyl Iodides to a AuI Complex
Bower, John F.,Cadge, Jamie A.,Russell, Christopher A.,Sparkes, Hazel A.
supporting information, p. 6617 - 6621 (2020/03/13)
The first isolated examples of intermolecular oxidative addition of alkenyl and alkynyl iodides to AuI are reported. Using a 5,5′-difluoro-2,2′-bipyridyl ligated complex, oxidative addition of geometrically defined alkenyl iodides occurs readily, reversibly and stereospecifically to give alkenyl-AuIII complexes. Conversely, reversible alkynyl iodide oxidative addition generates bimetallic complexes containing both AuIII and AuI centers. Stoichiometric studies show that both new initiation modes can form the basis for the development of C?C bond forming cross-couplings.
Assembly of Thiosubstituted Benzoxazoles via Copper-Catalyzed Coupling of Thiols with 5-Iodotriazoles Serving as Diazo Surrogates
Kotovshchikov, Yury N.,Latyshev, Gennadij V.,Kirillova, Elena A.,Moskalenko, Uliana D.,Lukashev, Nikolay V.,Beletskaya, Irina P.
supporting information, p. 9015 - 9028 (2020/08/14)
An efficient cascade approach to thiosubstituted benzoxazoles has been developed. The transformation starts with in situ generation of a diazo compound via annulation-triggered electrocyclic opening of the 1,2,3-triazole ring. The subsequent Cu-catalyzed trapping of diazo intermediates by various thiols affords the desired heterocycles in generally good yields of up to 91%. The protocol features very good functional group tolerance and is applicable to substrates with different electronic properties.
Chemoselective and stereospecific iodination of alkynes using sulfonium iodate(i) salt
Rao, Dodla S.,Reddy, Thurpu R.,Kashyap, Sudhir
supporting information, p. 1508 - 1518 (2018/03/08)
An efficient and highly chemoselective iodination of alkynes using a sulfonium iodate(i) electrophilc reagent under metal-free conditions has been realized. The reactivity of sulfonium iodate(i) salt could be significantly diverse in the presence of water
