52790-23-5Relevant academic research and scientific papers
Novel One-Pot Synthesis of Functionalized Quinolines from Isocyanides, Aniline, and Acetylene Dicarboxylate via Cu-Catalyzed Intramolecular C─H Activation Reactions
Nematpour, Manijeh,Rezaee, Elham,Jahani, Mehdi,Tabatabai, Sayyed Abbas
, p. 1254 - 1259 (2019)
The one-pot synthesis of a novel class of substituted quinoline derivatives with good yields is achieved via the Cu-catalyzed intramolecular C─H activation reaction between isocyanides, aniline, and acetylene dicarboxylate in MeCN at room temperature. The
Novel vitexin-inspired scaffold against leukemia
Ling, Taotao,Lang, Walter,Feng, Xiang,Das, Sourav,Maier, Julie,Jeffries, Cynthia,Shelat, Anang,Rivas, Fatima
supporting information, p. 501 - 510 (2018/02/15)
Acute lymphoblastic leukemia (ALL) is the most common type of leukemia in children. Up to a quarter of ALL patients relapse and face poor prognosis. To identify new compound leads, we conducted a phenotypic screen using terrestrial natural product (NP) fr
Efficient synthesis of the functionalized spiro[indoline-3,4'-pyridine] via four-component reaction
Sun, Jing,Wu, Qun,Zhang, Lijuan,Yan, Chaoguo
experimental part, p. 1548 - 1554 (2012/09/07)
An efficient synthetic procedure for the functionalized spiro[indoline-3,4'-pyridine] was developed via the four-component reactions of arylamines, acetylenedicarboxylates, isatins and malononitrile with triethylamine as the base catalyst. The advantages
A synthesis of 4-quinolone-3-carboxylic acids via pyrolysis of N- aryldioxopyrrolines
Mohri, Kunihiko,Kanie, Akihiko,Horiguchi, Yoshie,Isobe, Kimiaki
, p. 2377 - 2384 (2007/10/03)
A synthesis of 4-quinolone-3-carboxylic acids (8) was achieved by pyrolysis of 4,5-dimethoxycarbonyl-1-aryl-1H-pyrrole-2,3-diones (3) followed by selective demethoxycarbonylation of the resulting 2,3-dimethoxycarbonyl-4- quinolones (4) in excellent overall yields.
