52792-16-2

Upstream product

• 51044-12-3 (4-chlorobenzyl)triphenylphosphonium bromide 
• 52792-18-4 (E)-4-(4-chlorostyryl)benzaldehyde 
• 40817-03-6 p-xylenebis(triphenylphosphonium) dibromide 
• 104-88-1 4-chlorobenzaldehyde 
• 52577-04-5 p-xylylene-α,α'-bis(phosphonic acid dimethyl ester) 
• 589-87-7 1,4-bromoiodobenzene 
• 154230-29-2 (E)-4-chlorostyrylboronic acid 
• 623-27-8 terephthalaldehyde, 
• 106-42-3 para-xylene 
• 1073-67-2 4-vinylbenzyl chloride 
• 624-38-4 para-diiodobenzene 
• 1123168-01-3 1,3-bis[(E)-4-chlorostyryl]tetramethyldisiloxane 
• 622-95-7 4-chlorobenzyl bromide 
• 623-24-5 1,4-bis(bromomethyl)benzene 

Downstream Products

• 102441-25-8 1,4-bis-(4-chloro-phenethyl)-benzene 

Relevant academic research and scientific papers

Ruthenium-Sulfonamide-Catalyzed Direct Dehydrative Condensation of Benzylic C-H Bonds with Aromatic Aldehydes

The first catalytic dehydrative condensation of the benzylic C-H bonds of toluene and p-xylene with aromatic aldehydes is reported herein. This protocol provides highly atom-economical access to stilbene and p-distyrylbenzene derivatives, whereby water is the sole byproduct. The reaction is based on the deprotonation-functionalization of benzylic C-H bonds through η6-complexation of the arenes, which is realized for the first time using a catalytic amount of a transition metal activator. The key to the success of this method is the use of a sulfonamide anion as a catalyst component, which appears to facilitate not only the deprotonation of the benzylic C-H bonds but also the formation of a C-C bonds via an electrophilic tosylimine intermediate.

Synthesis of some new 1,4-distyrylbenzenes using immobilized palladium nanoparticles on silica functionalized morpholine as a recyclable catalyst

Some new 1,4-distyrylbenzene derivatives were synthesized by using immobilized palladium nanoparticles on silica-bonded N-propyl morpholine (PNP-SBNPM) as a heterogeneous catalyst. These one-pot reactions afforded a range of stereoselective, symmetrical (E)-1,4-distyrylbenzene derivatives with high yields (78-90%). The green catalyst system is recyclable and allows facile product isolation. The recycled catalyst could be reused six times without appreciable loss of catalytic activity. Georg Thieme Verlag Stuttgart · New York.

A convenient one-pot synthesis of bis[(E)-4-halostyryl]arene derivatives

A new convenient synthetic protocol for the one-pot stereoselective synthesis of bis[(E)-4-bromo(or chloro)styryl]arene derivatives via the sequential reaction of silylative-coupling of 4-halostyrenes with vinylsilanes followed by palladium-catalyzed cross-coupling 4-halostyrylsilanes with diiodoarenes, is described. The reaction leads to symmetrical bis[(E)-4-halostyryl]arene derivatives obtained in a stereocontrolled manner with high efficiency. Georg Thieme Verlag Stuttgart.

Palladium-catalyzed stereoselective synthesis of (E)-stilbenes via organozinc reagents and carbonyl compounds

In the presence of a catalytic amount of PdCl2(PPh 3)2 and a silylating agent, organozinc halides reacted with carbonyl compounds to give the corresponding (E)-stilbenes in good to excellent yields under mild conditions. The reaction mechanism is briefly discussed.

Platinum-catalyzed cross-couplings of organoboronic acids with aryl iodides

Tetrakis(triphenylphosphine)platinum in DMF was utilized as a mild catalyst for cross coupling reactions of organoboronic acids with aryl iodides. The present reactions exhibited excellent group-selectivity where couplings of organoboronic acids 2a-e with 4-bromo-1-iodobenzene (4) give 4-arylbromobenzenes 5a-b and 4-alkenylbromobenzenes 5c-e in excellent yields.