52824-93-8

Upstream product

• 4702-13-0 N-phthaloylglycine 
• 52824-45-0 (2-amino-4,5,6,7-tetrahydro-benzo[b]thiophen-3-yl)-o-tolyl-methanone 

Relevant academic research and scientific papers

Synthesis and pharmacological evaluation of 2,3 dihydro 1H thieno[2,3 e][1,4]diazepines

A series of 2,3 dihydro 1H thieno[2,3 e][1,4]diazepines was synthesized and evaluated for CNS activity. A new antianxiety screen for benzodiazepine like drugs was used along with the standard anticonvulsant test. Structure activity relationships are discussed. One compound, 1,3,6,7,8,9 hexahydro 5 phenyl 2H [1]benzothieno[2,3 e][1,4]diazepin 2 one monosulfate (CI 718), is undergoing clinical studies in man.