52827-07-3

Upstream product

• 52827-03-9 N-(3-chloro-phenyl)-N-nitroso-glycine 

Downstream Products

• 68657-31-8 alpha-(2-(2,2-dicyanovinyl)-2-(3-chlorophenyl)hydrazono)malononitrile 
• 4918-24-5 4-bromo-3-(3-chloro-phenyl)-sydnone 
• 85795-85-3 3-m-Chlorophenylsydnone-4-sulfonylchloride 
• 1346665-12-0 2-(m-chlorophenyl)-5-methyl-4-(4-phenylthiazol-2-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1346665-18-6 2-(m-chlorophenyl)-5-methyl-4[4-(p-nitrophenyl)thiazol-2-yl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1346665-24-4 4-[4-(p-bromophenyl)thiazol-2-yl]-2-(m-chlorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 269392-86-1 3-(3-chloro-phenyl)-5-methyl-3H-[1,3,4]oxadiazol-2-one 
• 57211-65-1 1-(3-chloro-phenyl)-1H-pyrazole 
• 1449770-58-4 2-(3-chlorophenyl)-5-methyl-4-(1H-tetrazol-1-yl)-2H-1,2,4-triazol-3(4H)-one 
• 666751-05-9 4-amino-2-(3-chloro-phenyl)-5-methyl-2,4-dihydro-[1,2,4]triazol-3-one 

Relevant academic research and scientific papers

Synthesis and evaluation of phenyl substituted sydnones as potential DPPH-radical scavengers

A series of phenyl substituted sydnones has been synthesized and their radical-scavenging activity has been studied on DPPH free radical. Out of eighteen compounds screened, nine compounds show interesting activity. A mechanism is presented whereby sydnones scavenge DPPH radical through donating H-atom at 4th-position. Its strong radical-scavenging activity mainly arises from 1, 2, 3-oxadiazolium-5-olate ring. Different substituents and their positions on the phenyl ring differently influence DPPH scavenging activity and therefore, may provide clues to design and develop better free-radical scavenging sydnones with multiple activities.