52830-65-6

Usage

Uses

Used in Pain Management:
Ketorolac is utilized as an analgesic agent for the treatment of moderate to severe pain, such as that resulting from surgical procedures, dental operations, or injuries. Its effectiveness in pain relief is attributed to its action on prostaglandin production, thereby reducing the sensation of pain.
Used in Inflammation Management:
In addition to its pain-relieving properties, ketorolac is also used as an anti-inflammatory agent. It helps in managing inflammation by curbing the production of prostaglandins, which are key mediators in the inflammatory process.
Used in Pharmaceutical Industry:
Ketorolac is used in the pharmaceutical industry for the development of various formulations aimed at short-term pain relief. It is available in oral tablets, injectable solutions, and ophthalmic solutions, with the latter specifically designed for treating eye pain and inflammation.
Used in Ophthalmology:
In the field of ophthalmology, ketorolac is used as an ophthalmic solution for the treatment of pain and inflammation in the eyes. Its application in this context is beneficial for conditions that cause discomfort and swelling in the ocular region.
However, it is important to note that the use of ketorolac is generally limited to short-term due to the potential risk of serious side effects, including gastrointestinal bleeding and kidney damage. This limitation underscores the need for careful consideration and medical supervision when using ketorolac for pain and inflammation management.

InChI:InChI=1/C19H21NO3/c1-4-20(5-2)14-10-11-15(13(3)12-14)18(21)16-8-6-7-9-17(16)19(22)23/h6-12H,4-5H2,1-3H3,(H,22,23)

Upstream product

• 85-44-9 phthalic anhydride 
• 91-67-8 N,N-diethyl-m-toluidine 

Downstream Products

• 52830-80-5 3-(2,4-bis(dimethylamino)-phenyl)-3-(2-methyl-4-(diethylamino)phenyl)phthalide 

Relevant academic research and scientific papers

Phthalide compound and a near infrared absorber and a recording material each comprising the same compound

A phthalide compound of general formula (I) and a near infrared absorber and a recording material each utilizing the phthalide compound are disclosed. STR1 wherein ring A represents a substituent group of the following formula STR2 where the other substituents are as defined in the disclosure. The near infrared absorber and the recorded image on the recording material absorb strongly the near infrared region with no appreciable absorption in the visible region of the spectrum. The near infrared absorber is colorless or pale in color and yet highly capable of absorbing near infrared radiation. The recorded image on the recording material can hardly be read with the eye but can be read with the OCR. Moreover, the effect on the developed shade of any concomitant color former in a recording material is minimal.

Phthalide compounds, and recording materials using the compounds

The invention relates to a phthalide compound of general formula (I), processes for its production, and recording materials utilizing the compound. (wherein R1 and R3 independently represent an alkyl group, a cycloalkyl group or an aralkyl group; R2 and R4 independently represent methyl or phenyl; R5 and R6 independently represent an alkyl group, a cycloalkyl group, an aralkyl group or an aryl group; R7 represents hydrogen, an alkyl group, an alkoxy group or a cyclo-alkoxy group; R5 and R6 may, taken together with the adjacent nitrogen atom, form a heterocyclic group). Recording materials utilizing the phthalide compound of the invention are suited for reading with any OCR equipped with a light source having an emission wavelength within the range of 570-780 nm.

Tri- or tetrasubstituted diphenylphthalides

Substituted 3,3-diphenylphthalides, useful as color precursors, particularly in the art of pressure-sensitive duplicating systems and heat-sensitive marking systems, are prepared by condensing substituted 2-benzoylbenzoic acids with substituted anilines.

Phenyljulolidinylphthalides

Substituted 3,3-diphenylphthalides, useful as color precursors, particularly in the art of pressure-sensitive duplicating systems, are prepared by condensing substituted 2-benzoylbenzoic acids with substituted anilines.