52835-62-8

Upstream product

• 1445-73-4 1-Methyl-4-piperidone 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 924831-12-9 2-amino-8-(4-bromobenzylidene)-4-(4-bromophenyl)-5,6,7,8-tetrahydro-6-methyl-4H-pyrano[3,2-c]pyridine-3-carbonitrile 
• 1174000-27-1 2-amino-8-(4-bromobenzylidene)-4-(4-bromophenyl)-5,6,7,8-tetrahydro-6-methyl-1,6-naphthyridine-3-carbonitrile 
• 1289514-45-9 (4R,8E)-2-amino-4-(4-bromophenyl)-8-(4-bromophenylmethylene)-5,6,7,8-tetrahydro-6-methyl-4H-pyrano[3,2-c]pyridine-3-carbonitrile 
• 1446347-74-5 (4S,8E)-2-amino-4-(4-bromophenyl)-8-(4-bromophenylmethylene)-5,6,7,8-tetrahydro-6-methyl-4H-pyrano[3,2-c]pyridine-3-carbonitrile 
• 1195986-36-7 C₂₉H₂₂Br₂N₄ 

Relevant academic research and scientific papers

High anti-cancer activity, low animal toxicity, and structure activity relationships of curcumin analogs

Background: Inhibition of cancer cell growth and low in vivo toxicity are two important criteria for the development of anti-cancer drugs. Curcumin is a promising candidate for developing novel anti-cancer drug analogs. The research group designed the 3,5

Magnetic graphene oxide anchored sulfonic acid as a novel nanocatalyst for the synthesis of N-aryl-2-amino-1,6-naphthyridines

Magnetic graphene oxide functionalized with sulfonic acid (Fe 3O4-GO-SO3H) was used as a new recyclable nanocatalyst for one-pot synthesis of N-aryl-2-amino-1,6-naphthyridine derivatives under solvent free conditions. The catalyst could be easily recovered from the reaction mixture by an external magnet and reused without significant decrease in activity even after 4 runs. This nanocatalyst exhibited better activities to other commercially available sulfonic acid catalysts.

An efficient method for synthesis of pyrano[3,2-c]pyridine derivatives under microwave irradiation

(Chemical Equation Presented) A series of pyrano[3,2-c]pyridine derivatives were synthesized via reactions of 3,5-dibenzylidenepiperidin-4-one and malononitrile in N,N-dimethylformamide under microwave irradiation. It is a simple, efficient, and promising

An efficient and chemoselective synthesis of 1,6-naphthyridines and pyrano[3,2-c]pyridines under microwave irradiation

A series of 1,6-naphthyridines and pyrano[3,2-c]pyridines were selectively synthesized via microwave-assisted reactions controlled by the nature of the solvent. This has resulted in an efficient and promising synthetic method for constructing the 1,6-naph