52840-12-7 Usage
Description
3-Ursodeoxycholic Acid-d5, also known as deuterated ursodeoxycholic acid (U850005), is a deuterated form of ursodeoxycholic acid, a major bile acid found in many vertebrates. It is characterized by its white solid appearance and is used in various applications due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
3-Ursodeoxycholic Acid-d5 is used as an anticholelithogenic agent for the treatment and prevention of cholesterol gallstones. It facilitates the solubilization of cholesterol and aids in its excretion, thus helping to dissolve gallstones and prevent their formation.
Used in Research and Development:
3-Ursodeoxycholic Acid-d5 is used as a labeled compound in research and development, particularly in the study of bile acid metabolism and its role in various physiological processes. The deuterium labeling allows for easier tracking and analysis of the compound in experimental settings.
Used in Drug Delivery Systems:
Similar to gallotannin, 3-Ursodeoxycholic Acid-d5 can be employed in novel drug delivery systems to enhance its applications and efficacy in treating various conditions related to bile acid metabolism and gallstone formation. The development of organic and metallic nanoparticles as carriers for this compound can improve its delivery, bioavailability, and therapeutic outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 52840-12-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,8,4 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 52840-12:
(7*5)+(6*2)+(5*8)+(4*4)+(3*0)+(2*1)+(1*2)=107
107 % 10 = 7
So 52840-12-7 is a valid CAS Registry Number.
52840-12-7Relevant articles and documents
Syntheses with stable isotopes: synthesis of deuterium and 13C labeled bile acids
Hachey,Szczepanik,Berngruber,Klein
, p. 703 - 719 (2007/10/16)
A series of 5β cholanic acids labeled with deuterium in the A ring were prepared by exchange labeling of the corresponding ketone by column chromatography on deuterated alumina. Factors affecting yield and labeling efficiency are discussed. 5β Cholanic acids labeled with 13C in the carboxyl position were prepared by treatment of the corresponding 23 chloro 24 norcholane with sodium cyanide 13C followed by alkaline hydrolysis of the nitrile. The intermediates in the synthesis were characterized by high resolution NMR spectroscopy. Mass spectra are also reported for the 13C labeled products.
