52846-87-4

Basic information

• Product Name: Benzaldehyde, 2-[(3-phenyl-2-propenyl)oxy]-
• CAS NO: 52846-87-4
• Molecular Formula: C16H14O2
• Molecular Weight: 238.286
• Mol File: 52846-87-4.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2-[(3-phenyl-2-propenyl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-[(3-phenyl-2-propenyl)oxy]-(52846-87-4)
• EPA Substance Registry System: Benzaldehyde, 2-[(3-phenyl-2-propenyl)oxy]-(52846-87-4)

Safety Data

• Hazardous Substances Data: 52846-87-4(Hazardous Substances Data)

Upstream product

• 90-02-8 salicylaldehyde 
• 4392-24-9 Cinnamyl bromide 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 
• 2687-12-9 cinnamyl chloride 
• 637-50-3 1-phenylpropene 

Downstream Products

• 1338832-14-6 2-methoxy-14-phenyl-5,6,12,13-tetrahydro-5,12-dioxa-7-azadibenzo[a,h]anthracen-6-one 
• 90404-57-2 2-(4-Chloro-phenyl)-3-phenyl-1,2,3,3a,4,9b-hexahydro-chromeno[4,3-c]pyrazole 
• 90404-55-0 3-Phenyl-2-p-tolyl-1,2,3,3a,4,9b-hexahydro-chromeno[4,3-c]pyrazole 

Relevant articles and documents

Synthesis of benzofused cyclobutaoxepanones: Via intramolecular annulation of o -cinnamyl chalcones

Intramolecular stereoselective annulation of o-cinnamyloxy chalcones provides two kinds of tricyclic benzofused cyclobutaoxepanones via the synthesized routes of DABCO/NBS (1,4-diazabicyclo[2.2.2]octane/N-bromosuccinimide)-mediated Baylis-Hillman type cyc

Asymmetric [2+2] photocycloadditionviacharge transfer complex for the synthesis of tricyclic chiral ethers

The asymmetric synthesis of chiral polycyclic ethers by an intramolecular [2+2] photocycloaddition is described. This process proceeded through a photocatalytically active iminium ion-based charge transfer (CT) complex under visible light irradiation. In this way a stereocontrolled [2+2] photocycloaddition is enabled leading to tricyclic products with good enantiomeric ratios.

Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-β Fibrils

A BF3·OEt2 catalyzed intramolecular Povarov reaction was used to synthesize 15 chromenopyridine fused thiazolino-2-pyridone peptidomimetics. The reaction works with several O-alkylated salicylaldehydes and amino functionalized thiazolino-2-pyridones, to generate polyheterocycles with diverse substitution. The synthesized compounds were screened for their ability to bind α-synuclein and amyloid β fibrils in vitro. Analogues substituted with a nitro group bind to mature amyloid fibrils, and the activity moreover depends on the positioning of this functional group.