52853-19-7Relevant articles and documents
Studies on the carbenium-iminium ions derived from N-methylmorpholine-N- oxide (NMMO)
Rosenau, Thomas,Potthast, Antje,Kosma, Paul
, p. 301 - 306 (2004)
Two carbenium-iminium ions, an exo-centered species 2 and a ring-centered form 3, are derived from the widely used oxidant and cellulose solvent N-methylmorpholine-N-oxide (1) by heterolytic degradation. 3 rearranges into 2 in the presence of water, in an endothermic, bimolecular reaction involving a highly organized transition state, which is the first example of a carbenium-iminium ion interconversion. The reaction mechanism was investigated by a combined approach consisting of trapping reactions, isotopic labeling, kinetic studies, and computations on the DFT level.
Substituted Sulfonamide Compounds
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Page/Page column 36-37, (2009/07/25)
Substituted sulfonamide compounds corresponding to the formula I wherein m, n, p, Q, R1, R2, R3, R4, X, Y and Z have the respective meanings defined herein, pharmaceutical compositions containing such compounds, a process for their preparation, and the use of such compounds for the treatment and/or inhibition of pain and other conditions mediated by bradykinin receptor 1 (B1R) and/or bradykinin receptor 2 (B2R).
4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5carboxamides as antiviral agents
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, (2008/06/13)
The invention provides a compound of formula I: wherein R1, R2, R3, and R4 have any of the values defined in the specification, or a pharmaceutically acceptable salt thereof, as well as processes and intermediat