52855-89-7

Upstream product

• 55628-82-5 1-(Phenylacetyl)imidazole 
• 762-42-5 dimethyl acetylenedicarboxylate 

Downstream Products

• 131471-28-8 6-Hydroxy-5-phenyl-8H-3,7,8,9b-tetraaza-cyclopenta[a]naphthalen-9-one 
• 131471-32-4 Acetic acid 6-oxo-5-phenyl-6,7-dihydro-3,7,8,9b-tetraaza-cyclopenta[a]naphthalen-9-yl ester 
• 131471-31-3 Acetic acid 9-oxo-5-phenyl-8,9-dihydro-3,7,8,9b-tetraaza-cyclopenta[a]naphthalen-6-yl ester 
• 131471-30-2 6-Methoxy-8-methyl-5-phenyl-8H-3,7,8,9b-tetraaza-cyclopenta[a]naphthalen-9-one 
• 131501-43-4 9-Methoxy-7-methyl-5-phenyl-7H-3,7,8,9b-tetraaza-cyclopenta[a]naphthalen-6-one 

Relevant academic research and scientific papers

Regiospecific Synthesis, Structure, and Fluorescence Properties of Highly Substituted Imidazopyridines and Pyridobenzimidazoles

1-(Arylacetyl)imidazoles 1 react with acetylenedicarboxylic esters to provide highly functionalized imidazopyridines 2 in up to 89percent yield.The scope and limitations of this novel condensation reaction have been investigated, and a mechanistic interpretation is presented.A strong effect on the yield of this reaction is observed for electron-donating and electron-withdrawing substituents in the para position of the aryl ring.Moreover, the transformation is shown to proceed in a regiospecific manner starting with 4,5-unsymmetrically substituted 1-(arylacetyl)imidazoles (1d-g) and is extended to the synthesis of the corresponding pyridobenzimazoles 12.The crystal structure of derivative 2a has been determined by X-ray analysis.Imidazopyridines 2 and pyridobenzimidazoles 12, obtained by this procedure, are highly fluorescent in the visible region with characteristically large Stokes shifts.

IMIDAZOLE DERIVATIVES. PART V. IMIDAZOPYRIDOPYRIDAZINE:SYNTHESIS,STRUCTURE,AND PRELIMINARY CHEMISTRY OF A NOVEL HETEROCYCLIC RING SYSTEM

Reaction of functionalized imidazopyridines with hydrazine hydrate to the novel imidazopyridopyridazine ring system is described

A Novel Synthesis of the Imidazopyridine Ring System

A simple one-step procedure furnishing regioselectively functionalized imidazopyridines (2) by a novel condensation reaction of 1-phenylacetylimidazole (1) with acetylenic dicarboxylic esters is described; the structure of one of the products (2a)