528570-73-2Relevant academic research and scientific papers
[2+2+2]-Co-cyclotrimerization 6-alkynylpurines with diynes: A method for preparation of 6-arylpurines
Turek, Pavel,Kotora, Martin,Hocek, Michal,Císa?ová, Ivana
, p. 785 - 788 (2003)
A novel approach to 6-arylpurines based on [2+2+2]-co-cyclotrimerization of 6-alkynylpurines with various α,ω-diynes is described. Co-cyclotrimerization is catalyzed by Ni- and Co-phosphine catalysts and their choice depends on the substitution pattern of the both reactants.
Preparation of highly substituted 6-arylpurine ribonucleosides by Ni-catalyzed cyclotrimerization. Scope of the reaction
Turek, Pavel,Novak, Petr,Pohl, Radek,Hocek, Michal,Kotora, Martin
, p. 8978 - 8981 (2007/10/03)
Transition metal complex catalyzed cocyclotrimerization of protected alkynylpurine ribonucleosides 1 with various diynes 2 gave rise to a series of 6-arylpurine nucleosides 3 that were further deprotected to free nucleosides 4. Generally, the best yields
