528587-60-2Relevant academic research and scientific papers
Synthesis of derivatives of (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) modified at the 1-aromatic moiety as novel NMDA receptor antagonists: The aromatic group is essential for the activity
Kazuta, Yuji,Tsujita, Ryuichi,Yamashita, Kanako,Uchino, Shigeo,Kohsaka, Shinichi,Matsuda, Akira,Shuto, Satoshi
, p. 3829 - 3848 (2007/10/03)
(1S,2R)-1-Phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC, 4a), which is a conformationally restricted analogue of antidepressant milnacipran [(±)-1], is a new class of potent noncompetitive NMDA receptor antagonists. A series of PPD
