528587-73-7

Basic information

• Product Name: (1S,5R)-2-oxo-1-(3-methylphenyl)-3-oxabicyclo[3.1.0]hexane
• Synonyms: (1S,5R)-2-oxo-1-(3-methylphenyl)-3-oxabicyclo[3.1.0]hexane
• CAS NO: 528587-73-7
• Molecular Weight: 188.226
• Mol File: 528587-73-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,5R)-2-oxo-1-(3-methylphenyl)-3-oxabicyclo[3.1.0]hexane(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,5R)-2-oxo-1-(3-methylphenyl)-3-oxabicyclo[3.1.0]hexane(528587-73-7)
• EPA Substance Registry System: (1S,5R)-2-oxo-1-(3-methylphenyl)-3-oxabicyclo[3.1.0]hexane(528587-73-7)

Safety Data

• Hazardous Substances Data: 528587-73-7(Hazardous Substances Data)

Upstream product

• 2947-60-6 3-methylbenzyl cyanide 
• 51594-55-9 (R)-(-)-epichlorohydrin 

Downstream Products

• 528588-05-8 (1S,2R)-1-(3-methylphenyl)-2-[(S)-1-azidopropyl]-N,N-diethylcyclopropanecarboxamide 
• 528587-97-5 (1S,2R)-1-(3-methylphenyl)-2-[(S)-1-hydroxypropyl]-N,N-diethylcyclopropanecarboxamide 
• 528587-89-5 (1S,2R)-1-(3-methylphenyl)-2-formyl-N,N-diethylcyclopropanecarboxamide 
• 528588-21-8 (1S,4S,5R)-2-oxo-4-ethyl-1-(3-methylphenyl)-3-oxabicyclo[3.1.0]hexane 
• 528587-81-7 (1S,2R)-1-(3-methylphenyl)-2-(hydroxymethyl)-N,N-diethylcyclopropanecarboxamide 

Relevant articles and documents

Synthesis of derivatives of (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) modified at the 1-aromatic moiety as novel NMDA receptor antagonists: The aromatic group is essential for the activity

(1S,2R)-1-Phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC, 4a), which is a conformationally restricted analogue of antidepressant milnacipran [(±)-1], is a new class of potent noncompetitive NMDA receptor antagonists. A series of PPD