528594-63-0 Usage
Explanation
The compound's full name, which describes its structure and composition.
Explanation
The process through which the compound is formed, involving the reaction between an acid and an alcohol.
Explanation
The different functional groups present in the molecule, which contribute to its chemical properties and reactivity.
Explanation
The molecular formula represents the number of carbon (C), hydrogen (H), nitrogen (N), and oxygen (O) atoms in the compound.
Explanation
The mass of one mole of the compound, calculated from its molecular formula.
Explanation
The physical appearance of the compound in its pure form.
Explanation
The compound's ability to dissolve in specific solvents, which is important for its use in chemical reactions and purification processes.
Explanation
The compound's resistance to decomposition or reaction under typical conditions, making it suitable for use in research and synthesis.
Explanation
The various fields in which the compound is utilized, highlighting its versatility and importance in chemical and pharmaceutical research.
Derivation
Esterification of 1,4-Dioxa-7-azaspiro[4.5]decane-7-carboxylic acid with phenylMethyl alcohol
Functional Groups
Ester, Carboxylic Acid, Phenyl, and Methyl groups
Molecular Weight
263.29 g/mol
Appearance
Colorless to pale yellow solid
Solubility
Soluble in organic solvents like ethanol, methanol, and dichloromethane
Stability
Stable under normal laboratory conditions
Applications
Precursor in organic synthesis, pharmaceutical research, and potential use in the development of new medications
Check Digit Verification of cas no
The CAS Registry Mumber 528594-63-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,2,8,5,9 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 528594-63:
(8*5)+(7*2)+(6*8)+(5*5)+(4*9)+(3*4)+(2*6)+(1*3)=190
190 % 10 = 0
So 528594-63-0 is a valid CAS Registry Number.
528594-63-0Relevant academic research and scientific papers
AZACARBAZOLE BTK INHIBITORS
-
Page/Page column 52, (2016/10/31)
The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula (I), or pharmaceutically acceptable salts thereof, wherein CH, R1, R1a, R1b, R2, R3, and the subscripts m1, m2, p, q, and t are as set forth herein. The present invention also provides pharmaceutical compositions comprising these compounds and their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula (I) in the treatment of Btk mediated disorders.
Convenient preparation of cyclic acetals, using diols, TMS-source, and a catalytic amount of TMSOTf
Kurihara, Masaaki,Hakamata, Wataru
, p. 3413 - 3415 (2007/10/03)
With use of diol, alkoxysilane, and a catalytic amount of trimethylsilyl trifluoromethanesulfonate (TMSOTf), carbonyl compounds are converted to acetals in good yields under mild conditions. This procedure, which was carried out without synthesizing the silylated diols, is a more convenient adaptation of Noyori's method. This acetalization applies to not only simple but also conjugated carbonyl compounds. Moreover, various TMS compounds, including solid supported compounds, are effective for this method instead of alkoxylsilane.
