528602-90-6

Basic information

• Product Name: C₃₄H₃₈N₂O₂
• CAS NO: 528602-90-6
• Molecular Weight: 506.688
• Mol File: 528602-90-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₄H₃₈N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₄H₃₈N₂O₂(528602-90-6)
• EPA Substance Registry System: C₃₄H₃₈N₂O₂(528602-90-6)

Safety Data

• Hazardous Substances Data: 528602-90-6(Hazardous Substances Data)

Upstream product

• 10022-79-4 1-phenyl-4,9-dihydro-3H-β-carboline 
• 126378-43-6 (1R,2S,5R)-(-)-8-phenylmenthyl chloroformate 

Relevant articles and documents

Palladium asymmetric reduction of β-carboline imines mediated by chiral auxiliaries assisted by microwave irradiation

An alternative synthetic approach for the introduction of chirality in β-carboline moiety through in situ reduction of N-acyliminium ion intermediates generated from imine 2 and chloroformate of 8-phenylmenthyl as chiral auxiliary was achieved. The method applied microwave-assisted irradiation and used PdCl2/Et3SiH protocol as a mild reducing agent, which decreased reaction times to minutes when compared to the conventional thermal reactions. The diastereoselectivity (4-12:1) of the reduction produced R-amines, which were assigned after chiral auxiliary removal and spectroscopic data compared to products obtained from Noyori asymmetric hydrogenation catalyst.