52881-31-9Relevant academic research and scientific papers
Synthesis of 3 substituted thieno[2,3 d]pyrimidin 4(3H) one 2 mercaptoacetic acids and their ethyl esters for pharmacological screening
Devani,Shishoo,Pathak,Parikh,Shah,Padhya
, p. 660 - 664 (2007/10/08)
3 Substituted thieno[2,3 d]pyrimidin 4(3H) one 2 mercaptoacetic acids and their ethyl esters were synthesized from 2 mercaptothieno[2,3 d]pyrimidin 4 (3H) ones, which were obtained by cyclization of thienylthioureas in acidic medium. Analgesic, anti inflammatory, and anticonvulsant activities were found in some of these compounds. Significant antimicrobial activity was exhibited by thienylthioureas.
Synthesis of 2-methylene-2,3-dihydro-and 2-methyl-5H-thiazolo[3.2-a]thieno[2.3-d]pyrimidines
Sauter,Deinhammer,Danksagmueller
, p. 863 - 868 (2007/10/05)
The title substances and their [1]benzothieno analogues were synthesized by reaction of 3-allyl-2-mercapto-([1]benzo)thieno-[2.3-d]pyrimidine-4(3 H)-ones with Br2 to 2-bromomethyl-2.3-dihydro-thiazolo[3.2-a]([1]benzo-)thieno[2.3-d]pyrimidine-5-ones, which on treatment with morpholine did not give the corresponding morpholine derivatives but elimination to the exocyclic double bond. These 2-methylene-2.3-dihydro-products were isomerized by H2SO4 to the corresponding 2-methyl compounds.
