528852-53-1Relevant academic research and scientific papers
Syntheses of sphingosine-1-phosphate stereoisomers and analogues and their interaction with EDG receptors.
Lim, Hyun Suk,Oh, Yong Seok,Suh, Pann Ghill,Chung, Sung Kee
, p. 237 - 240 (2003)
Sphingosine-1-phosphate (S1P) is considered to be an important regulator of diverse biological processes acting as a natural ligand to EDG receptors. As a preliminary study to develop potent and selective agonist and antagonist for EDG receptors, we report synthesis of S1P stereoisomers and analogues and their binding affinities to EDG-1, -3, and -5.
