52913-15-2Relevant academic research and scientific papers
1,3,4,5-Tetraamino-1,2,4-triazolium Cation: An Energetic Moiety
Yocca, Sebastian R.,Yount, Joseph,Zeller, Matthias,Byrd, Edward F. C.,Piercey, Davin G.
, p. 9645 - 9652 (2021/06/30)
The amination of 3,4,5-triamino-1,2,4-triazole with O-tosylhydroxylamine yielded the nitrogen-rich 1,3,4,5-tetraamino-1,2,4-triazolium cation as its tosylate salt. Subsequent metathesis reactions produced energetic salts with various energetic anions, inc
O - substituted hydroxylamine hydrochloride and its preparation method (by machine translation)
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Paragraph 0107-0109, (2018/10/11)
The present invention provides a O - substituted hydroxylamine hydrochloride and its preparation, wherein the preparation method comprises the following steps: step S1, to the acetyl hydroximic acid ethyl ester in ethanol solution of adding sodium hydroxide, in addition at the same time instillment halohydrocarbon, chloride or acyl chloride substitution reaction to take place, then added to the water in order to separate out the O - substituted [...]; step S2, the said O - substituted [...] adding hydrochloric acid solution in order to produce reflux reaction O - substituted hydroxylamine hydrochloride. According to the embodiment of the invention of the O - substituted hydroxylamine hydrochloride of the preparation method, high purity of the product can be obtained, and the method is safe, easy to process, the process is simple, and is suitable for industrial production. (by machine translation)
Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment 13. Synthesis and profiling of a novel amminium prodrug of the HIV-1 attachment inhibitor BMS-585248
Regueiro-Ren, Alicia,Simmermacher-Mayer, Jean,Sinz, Michael,Johnson, Kim A.,Huang, Xiaohua Stella,Jenkins, Susan,Parker, Dawn,Rahematpura, Sandhya,Zheng, Ming,Meanwell, Nicholas A.,Kadow, John F.
, p. 1670 - 1676 (2013/04/23)
In vitro studies suggested that the ammonium salt 2 could be a viable prodrug of the HIV-1 attachment inhibitor 1. Increased systemic exposure of the parent drug 1 following oral administration of the amminium salt 2 when compared to similar studies using
Weak Interactions in Crystals: 4,4'-Di(tert-butyl)-N-N'-bipyridinium Diperchlorate - A Biphenyl Analogue with Perpendicular Pyridine Rings
Bock, Hans,Nick, Sabine,Naether, Christian,Bensch, Wolfgang
, p. 557 - 563 (2007/10/03)
Oxidation of substituted N-aminopyridinium compounds yields bipyridinium salts.After anion exchange Br(1-) --> ClO4(1-), it was possible to grow single crystals from the 4,4'-di(tert-butyl)derivative.The structure determined at 100 K shows a dihedral angl
