5292-53-5Relevant articles and documents
Bifunctional acid-base ionic liquid organocatalysts with a controlled distance between acid and base sites
Boronat, Mercedes,Climent, Maria J.,Corma, Avelino,Iborra, Sara,Monton, Raquel,Sabater, Maria J.
, p. 1221 - 1231 (2010)
Bifunctional acid-base ionic liquid organocatalysts with different distances between the two sites have been synthesised, and their activity for the Knoevenagel condensation has been tested. As has been found to be the case with enzymes, the distance betw
Synthesis, characterization, and catalytic activity of ionic liquids based on biosources
Moriel,García-Suárez,Martínez,García,Montes-Morán,Calvino-Casilda,Ba?ares
, p. 4877 - 4881 (2010)
New room-temperature ionic liquids were synthesized from natural and easily available feedstocks (choline hydroxide and amino acids) following an economical and green route in which the only by-product was water. They were successfully applied as catalyst
Mg/Al-CO3 layered double hydroxide nanorings
Yang, Miaosen,Liu, Junfeng,Chang, Zheng,Williams, Gareth R.,O'Hare, Dermot,Zheng, Xuehan,Sun, Xiaoming,Duan, Xue
, p. 14741 - 14746 (2011)
Mg/Al-CO3 Layered Double Hydroxide (LDH) nanorings with a 750 nm exterior diameter and 250 nm interior diameter were synthesized in an organic/water solvent system via a urea hydrolysis method, using Mg 10(OH)18Cl2/s
Alkaline carbons as effective catalysts for the microwave-assisted synthesis of N-substituted-gamma-lactams
Calvino-Casilda,Martín-Aranda,López-Peinado
, p. 73 - 81 (2011)
The selective construction of new CC or Cheteroatom bonds is frequently the fundamental step in the synthesis of derivatives with high added value. In particular, molecules with CN bonds are of great interest due to their widespread use and intrinsic impo
A facile, efficient and solvent-free titanium (IV) ethoxide catalysed knoevenagel condensation of aldehydes and active methylenes
Ramaiah, Manjunatha M.,Shivananju, Nanjunda Swamy,Shubha, Priya Babu
, p. 107 - 115 (2020/02/04)
Titanium ethoxide has been employed as a novel and efficient reagent for the Knoevenagel condensation of aldehydes with active methylenes such as diethyl malonate and ethyl cyanoacetate under solvent free conditions to afford substituted olefins in high to excellent yields. The reaction is suitable for a variety of aromatic, aliphatic and heteroaromatic aldehydes with various active methylenes. Parallel to this, microwave irradiation has been utilized to achieve improved reaction rates and enhanced yields. Herein, we illustrated a convenient method for the preparation of α,β-unsaturated compounds using both conventional and microwave irradiation methods. An efficient and solvent free Knoevenagel condensation between aldehydes and active methylenes was developed using titanium ethoxide. The procedure proved to be successful with a wide range of substrates such as aromatic, aliphatic and heterocyclic aldehydes and various active methylenes to afford substituted olefins. The reaction was also carried out under microwave irradiation to accomplish the corresponding olefins with improved reaction rates, yields and cleaner reaction profiles.We have developed an efficient and novel methodology for the synthesis of olefinic compounds by Knoevenagel condensation under solvent-free conditions using titanium ethoxide, for the first time, as a reagent as well as a solvent. This method is appropriate for the synthesis of a variety of aromatic aldehydes containing various electron-donating and withdrawing groups, aliphatic and heteroaromatic aldehydes. The significant advantages offered by this methodology could be applied to various active methylenes in order to offer the corresponding Knoevenagel products. Thus, we believe that this method delivers high conversions, cleaner reaction profiles under solvent-free reaction conditions and shorter reaction times, all of which make it a very useful and attractive approach for the preparation of a wide range of substituted olefins.
Highly active hybrid mesoporous silica-supported base organocatalysts for C–C bond formation
Erigoni,Hernández-Soto,Rey,Segarra,Díaz
, p. 227 - 236 (2019/10/28)
New base hybrid catalysts, based on silyl-derivatives of molecules carrying amino, diamino, pyrrolidine, pyrazolium and imidazolium functionalities have been successfully achieved through post synthetic grafting onto M41S-type support. Different character
