529484-01-3

Basic information

• Product Name: benzyl (3S)-c-6-[(5'S)-5'-(tert-butyloxycarbonyl)-2'-oxo-pyrrolidin-1'-yl]-t-4,t-5-dihydroxy-r-3-methyl-1,2-oxazinane-2-carboxylate
• Synonyms: benzyl (3S)-c-6-[(5'S)-5'-(tert-butyloxycarbonyl)-2'-oxo-pyrrolidin-1'-yl]-t-4,t-5-dihydroxy-r-3-methyl-1,2-oxazinane-2-carboxylate
• CAS NO: 529484-01-3
• Molecular Weight: 450.489
• Mol File: 529484-01-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl (3S)-c-6-[(5'S)-5'-(tert-butyloxycarbonyl)-2'-oxo-pyrrolidin-1'-yl]-t-4,t-5-dihydroxy-r-3-methyl-1,2-oxazinane-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (3S)-c-6-[(5'S)-5'-(tert-butyloxycarbonyl)-2'-oxo-pyrrolidin-1'-yl]-t-4,t-5-dihydroxy-r-3-methyl-1,2-oxazinane-2-carboxylate(529484-01-3)
• EPA Substance Registry System: benzyl (3S)-c-6-[(5'S)-5'-(tert-butyloxycarbonyl)-2'-oxo-pyrrolidin-1'-yl]-t-4,t-5-dihydroxy-r-3-methyl-1,2-oxazinane-2-carboxylate(529484-01-3)

Safety Data

• Hazardous Substances Data: 529484-01-3(Hazardous Substances Data)

Upstream product

• 175789-29-4 (3S,6S)-6-((S)-2-tert-Butoxycarbonyl-5-oxo-pyrrolidin-1-yl)-3-methyl-3,6-dihydro-[1,2]oxazine-2-carboxylic acid benzyl ester 

Downstream Products

• 35418-16-7 L-t-butyl pyroglutamate 

Relevant articles and documents

Asymmetric synthesis of potent glycosidase and very potent α-mannosidase inhibitors: 4-amino-4-deoxy-L-erythrose and 4-amino-4,5-dideoxy-L-ribose

Pyrrolidine amino-sugars, cyclic iminoalditols as well as linear aminoalditols in 4-amino-L-erythrose and 4-amino-5-deoxy-L-ribose series were synthesised by asymmetric hetero-Diels-Alder reaction followed by chemical transformations. 4-Amino-4-deoxy-L-erythrose and 4-amino-4,5-dideoxy-L-ribose were potent β-D-glucosidase, α-D-mannosidase, α- and β-D-galactosidase inhibitors. We have shown that the ribose derivative was a very potent inhibitor of α-D-mannosidase.