529486-26-8 Usage
Uses
Used in Pharmaceutical Industry:
(2S,1μS, 2μS)-Pyrrolidine-2-carboxylic acid (2-hydroxy-1,2-diphenyl-ethyl)amide is used as a catalyst for the synthesis of α-hydroxyaminocarbonyl compounds. This application is due to its ability to facilitate the N-nitroso aldol reaction between aldehydes and nitrosobenzenes, leading to the formation of valuable intermediates in the pharmaceutical industry.
Used in Chemical Synthesis:
In the field of chemical synthesis, (2S,1μS, 2μS)-Pyrrolidine-2-carboxylic acid (2-hydroxy-1,2-diphenyl-ethyl)amide is used as a catalyst for direct aldol reactions. This involves the reaction of aldehydes with chloroacetones, methylthio-, and fluoroacetones. (2S,1μS, 2μS)-Pyrrolidine-2-carboxylic acid (2-hydroxy-1,2-diphenyl-ethyl)amide's catalytic properties enable the formation of important synthetic building blocks, which can be further utilized in the development of various chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 529486-26-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,2,9,4,8 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 529486-26:
(8*5)+(7*2)+(6*9)+(5*4)+(4*8)+(3*6)+(2*2)+(1*6)=188
188 % 10 = 8
So 529486-26-8 is a valid CAS Registry Number.
529486-26-8Relevant academic research and scientific papers
Asymmetric conjugate addition of ketones to β-nitrostyrenes by means of 1,2-amino-alcohol-derived prolinamides as bifunctional catalysts
Almasi, Diana,Alonso, Diego A.,Gomez-Bengoa, Enrique,Nagel, Yvonne,Najera, Carmen
, p. 2328 - 2343 (2008/02/08)
Different L-prolinamides 21, prepared from L-proline and chiral β-amino alcohols are active bifunctional catalysts for the direct nitro-Michael addition of ketones to β-nitrostyrenes. In particular, catalyst 21e, prepared from L-proline and (1S,2R?)-cis-1
Novel small organic molecules for a highly enantioselective direct aldol reaction
Tang, Zhuo,Jiang, Fan,Yu, Luo-Ting,Cui, Xin,Gong, Liu-Zhu,Mi, Ai-Qiao,Jiang, Yao-Zhong,Wu, Yun-Dong
, p. 5262 - 5263 (2007/10/03)
Novel organic molecules containing an l-proline amide moiety and a terminal hydroxyl for catalyzing direct asymmetric aldol reactions of aldehydes in neat acetone are designed and prepared. Catalyst 3d, prepared from l-proline and (1S,2S)-diphenyl-2-amino
