52955-49-4Relevant academic research and scientific papers
METHODS AND COMPOSITIONS FOR DETECTING OR MEASURING CASPASES OR APOPTOSIS
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Paragraph 0444; 0445; 0446, (2019/10/20)
Provided herein are compounds, enzyme substrates, compositions, kits, uses, and methods for detecting the presence or absence of a caspase enzyme, measuring the activity of a caspase enzyme, or detecting the presence or absence of apoptosis. The detection or measurement can occur through intracellular cleavage of a compound or enzyme substrate, which can lead to an increase in fluorescence, e.g., in the violet or red channel, through liberation of a nucleic acid binding dye from a peptide, such as liberation of a DNA-binding dye from a negatively charged peptide comprising a sequence recognized and cleaved by a caspase
Photocyclization of ω-Anilinoalkylphthalimides: A Photochemical Macrocyclic Synthesis
Machida, Minoru,Takechi, Haruko,Kanaoka, Yuichi
, p. 1579 - 1587 (2007/10/02)
Upon irradiation, a homologous series of N-phthalimides 5, having a nonconjugated bichromopholic system, undergoes regioselective remote photocyclization to give medium- to large-sized (up to twenty-two-membered) diazacyclols 6.Key
