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2-(4-Trifluoromethyl-phenyl)-ethylamine hydrochloride is a chemical compound that features a 4-Trifluoromethyl-phenyl group attached to an ethylamine moiety. It is typically found in the form of a hydrochloride salt. 2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE HYDROCHLORIDE is of interest in research and pharmaceutical applications due to the presence of the trifluoromethyl group, which is often used as a bioisostere in medicinal chemistry. The ethylamine functionality is also prevalent in many pharmacologically active compounds, contributing to the compound's potential uses.

52997-74-7

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52997-74-7 Usage

Uses

Used in Pharmaceutical Research:
2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE HYDROCHLORIDE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its trifluoromethyl group and ethylamine moiety provide a structural foundation that can be further modified to develop new drugs with potential therapeutic applications.
Used in Medicinal Chemistry:
2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE HYDROCHLORIDE is used as a building block in the design of new molecules with potential medicinal properties. The trifluoromethyl group can impart unique electronic and steric effects, which can influence the compound's interaction with biological targets, such as enzymes or receptors.
Used in Chemical Synthesis:
2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE HYDROCHLORIDE is used as a reagent in the synthesis of complex organic molecules. Its functional groups can participate in various chemical reactions, allowing for the creation of a wide range of compounds with different properties and applications.
Note: The specific applications and uses mentioned above are inferred based on the general properties of the compound and its potential relevance in the fields of pharmaceutical research and medicinal chemistry. Actual applications may vary and would require further experimental validation and research.

Check Digit Verification of cas no

The CAS Registry Mumber 52997-74-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,9,9 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 52997-74:
(7*5)+(6*2)+(5*9)+(4*9)+(3*7)+(2*7)+(1*4)=167
167 % 10 = 7
So 52997-74-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H10F3N.ClH/c10-9(11,12)8-3-1-7(2-4-8)5-6-13;/h1-4H,5-6,13H2;1H

52997-74-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[4-(trifluoromethyl)phenyl]ethanamine,hydrochloride

1.2 Other means of identification

Product number -
Other names 2-[4-(trifluoromethyl)phenyl]ethanamine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52997-74-7 SDS

52997-74-7Downstream Products

52997-74-7Relevant academic research and scientific papers

Regio- and stereoselective hydroamination of alkynes using an ammonia surrogate: Synthesis of N -Silylenamines as reactive synthons

Lui, Erica K. J.,Brandt, Jason W.,Schafer, Laurel L.

supporting information, p. 4973 - 4976 (2018/04/24)

An anti-Markovnikov selective hydroamination of alkynes with N-silylamines to afford N-silylenamines is reported. The reaction is catalyzed by a bis(amidate)bis(amido)Ti(IV) catalyst and is compatible with a variety of terminal and internal alkynes. Stoichiometric mechanistic studies were also performed. This method easily affords interesting N-silylenamine synthons in good to excellent yields and the easily removable silyl protecting group enables the catalytic synthesis of primary amines.

Anti-thrombotic peptide and pseudopeptide derivatives

-

, (2008/06/13)

Disclosed are novel peptide and pseudopeptide derivatives and pharmaceutical compositions thereof that inhibit platelet aggregation and thrombus formation in mammalian blood.

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