53-40-7 Usage
Uses
Used in Neuropharmacology:
(2beta,3alpha,5alpha)-3-hydroxy-2-(morpholin-4-yl)pregnan-20-one is used as a neurosteroid for its potential therapeutic applications in the treatment of various neuropsychiatric disorders. Its ability to modulate the GABAA receptor results in sedative, anxiolytic, and anticonvulsant effects, making it a promising candidate for conditions such as anxiety disorders, depression, and PTSD.
Used in Neuroprotection and Neurogenesis:
(2beta,3alpha,5alpha)-3-hydroxy-2-(morpholin-4-yl)pregnan-20-one is also used in research for its potential role in promoting neurogenesis and neuroprotection. Its effects on the brain's inhibitory neurotransmitter GABA suggest that it may have the ability to support the growth and protection of neurons, which could be beneficial in the development of treatments for neurodegenerative diseases and other conditions affecting brain health.
Check Digit Verification of cas no
The CAS Registry Mumber 53-40-7 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 53-40:
(4*5)+(3*3)+(2*4)+(1*0)=37
37 % 10 = 7
So 53-40-7 is a valid CAS Registry Number.
53-40-7Relevant academic research and scientific papers
Anderson, Alison,Boyd, Andrew C.,Byford, Alan,Campbell, Alexander C.,Gemmell, David K.,Hamilton, Niall M.,Hill, David R.,Hill-Venning, Claire,Lambert, Jeremy J.,Maidment, Maurice S.,May, Valerie,Marshall, Richard J.,Peters, John A.,Rees, David C.,Stevenson, Donald,Sundaram, Hardy
, p. 1668 - 1681 (1997)
(3α,5α)-3-Hydroxypregnan-20-ones and (3α,5α)-3-hydroxypregnane- 11,20-diones bearing a 2β-morpholinyl substituent were synthesized, and the utility of these steroids as anesthetic agents was evaluated through determination of their potency and duration of
