530085-88-2Relevant academic research and scientific papers
Trifluoromethylation of allylsilanes under copper catalysis
Mizuta, Satoshi,Galicia-Lopez, Oscar,Engle, Keary M.,Verhoog, Stefan,Wheelhouse, Katherine,Rassias, Gerasimos,Gouverneur, Veronique
supporting information; experimental part, p. 8583 - 8587 (2012/08/14)
Branched allylic CF3 products are accessible by copper-catalyzed trifluoromethylation of allylsilanes with the Togni reagent I. The silyl group is critical to control the outcome of this reaction because in its absence, a product of addition be
Asymmetric oxidation of enol phosphates to α-hydroxy ketones using Sharpless reagents and a fructose derived dioxirane
Krawczyk, Ewa,Mielniczak, Grazyna,Owsianik, Krzysztof,?uczak, Jerzy
, p. 1480 - 1489 (2013/01/15)
The asymmetric oxidation of a variety of differently substituted, acyclic and cyclic enol phosphates using the Sharpless AD-reagents AD-mix-α and AD-mix-β, and a fructose derived chiral ketone as a catalyst, afforded the corresponding α-hydroxy ketones in high enantioselectivity and good yield. The influence of steric and electronic factors of the substrates on the facial stereoselectivity in the reported oxidations was studied.
Asymmetric oxidation of enol phosphates to α-hydroxy ketones by?(salen)manganese(III) complex. Effects of the substitution pattern of enol phosphates on the stereochemistry of oxygen?transfer
Koprowski, Marek,?uczak, Jerzy,Krawczyk, Ewa
, p. 12363 - 12374 (2007/10/03)
This paper presents a study of enantioselective catalytic oxidation of a variety of differently substituted, cyclic (E) and acyclic (Z)-enol phosphates. The asymmetric oxidation of acyclic (Z)-enol phosphates containing alkoxy substituents in the phosphate group 2a, c, e-g, i, and j and Z-configured enol phosphates containing aryloxy substituents in the phosphate group 2b, d, and h afforded optically active α-hydroxy ketones 4a-j of opposite configuration with good to high enantioselectivity. The influence of electronic and steric effects of the enol phosphate substituents on the stereoselectivity of oxidation was studied.
The preparation of alkylaryldichlorocyclopropanol phosphates
Xi, Qi,Lin, Xingji,Chang, Jianhua,Ding, Yixiang
, p. 47 - 54 (2007/10/03)
In the present article we report the preparation of alkylaryldichlorocyclopropanol phosphates by the addition of dichlorocarbene to enol phosphates of propiophenone and cyclohexanone with steric hinderance. The stereoselectivity of enol phosphates and the effect of substituents on the carbene addition rate are discussed.
