5301-03-1 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
5-Bromomethyl-3-(3-nitrophenyl)-isoxazole is used as a building block for the synthesis of more complex molecules with potential medicinal properties. The presence of the bromomethyl and 3-nitrophenyl groups makes it a valuable component in the development of new drugs.
Used in Medicinal Chemistry:
5-Bromomethyl-3-(3-nitrophenyl)-isoxazole is used as a promising candidate for further exploration in medicinal chemistry. The isoxazole ring structure has been implicated in various biological activities, making 5-Bromomethyl-3-(3-nitrophenyl)-isoxazole a valuable tool for studying and developing new pharmaceutical agents.
Check Digit Verification of cas no
The CAS Registry Mumber 5301-03-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,0 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5301-03:
(6*5)+(5*3)+(4*0)+(3*1)+(2*0)+(1*3)=51
51 % 10 = 1
So 5301-03-1 is a valid CAS Registry Number.
5301-03-1Relevant academic research and scientific papers
Synthesis and characterization of 2-Alkyl -5-{4-[(3-nitrophenyl- 5isoxazolyl)methoxy]phenyl}-2H-tetrazoles
Mirzaei,Edjlali
experimental part, p. 685 - 694 (2010/10/20)
Heteroaryl substituted analogs of antirhnoviral (A), was prepared by a convergent approach. 3-Nitrophenyl-5bromooromethylisoxazoles 5a-b were synthesized by [3+2] cycloaddition of 3-(benzoyloxy)-propyne 2 to in situ generated arylnitrile oxides followed by deprotection of cycloadducts 3a-b and bromination of the resulting alcohols 4a-b. Coupling of 3nitrophenyl-5- bromooromethylisoxazoles (5a-b) with 4-[5-(2-alkyl-2H-tetrazolyl)]phenols (6a-d) in N-methylpyrrolidinone under mild conditions afforded a new series of 2-alkyl-5-{4-[1-(3-nitrophenyl-5-isoxazolyl)methyloxy]phenyl}-2H-tetrazoles (7a-h) in high yields. The structures of the synthesized compounds were confirmed by their 1H NMR, Mass spectral, and Elemental Analysis data.
